MEK-7(Phospho Ser271) Polyclonal Antibody

The protein encoded by this gene is a dual specificity protein kinase that belongs to the MAP kinase kinase family. This kinase specifically activates MAPK8/JNK1 and MAPK9/JNK2, and this kinase itself is phosphorylated and activated by MAP kinase kinase kinases including MAP3K1/MEKK1, MAP3K2/MEKK2,MAP3K3/MEKK5, and MAP4K2/GCK. This kinase is involved in the signal transduction mediating the cell responses to proinflammatory cytokines, and environmental stresses. Alternative splicing results in multiple transcript variants.

The MEK-7(Phospho Ser271) Polyclonal Antibody is a highly specific and sensitive tool designed for the detection and quantification of MEK-7 protein phosphorylated at Serine 271. This antibody is produced using advanced polyclonal antibody production techniques, ensuring high affinity and specificity towards the target protein.

MEK-7, also known as MAP2K7 or MKK7, is a member of the mitogen-activated protein kinase kinase (MAPKK) family. It plays a crucial role in the regulation of various cellular processes, including cell proliferation, differentiation, and apoptosis. Phosphorylation of MEK-7 at Serine 271 has been implicated in the activation of downstream signaling pathways, such as the c-Jun N-terminal kinase (JNK) pathway.

The MEK-7(Phospho Ser271) Polyclonal Antibody has been extensively validated for its performance in various applications, including Western blotting, immunohistochemistry, and immunofluorescence. It exhibits excellent sensitivity and specificity, enabling accurate and reliable detection of phosphorylated MEK-7 protein in complex biological samples.

This antibody is supplied as a liquid formulation, ready for immediate use. It is provided in a convenient size and concentration, allowing for easy handling and storage. The MEK-7(Phospho Ser271) Polyclonal Antibody is suitable for use in both research and diagnostic applications, aiding in the understanding and diagnosis of diseases associated with dysregulated MEK-7 signaling.

In summary, the MEK-7(Phospho Ser271) Polyclonal Antibody is a valuable tool for researchers and clinicians studying the role of MEK-7 phosphorylation in cellular processes and disease pathogenesis. Its high specificity, sensitivity, and versatility make it an essential component of any laboratory or diagnostic setting.