MEK Kinase-1(Phospho Thr1402) Polyclonal Antibody

The protein encoded by this gene is a serine/threonine kinase and is part of some signal transduction cascades, including the ERK and JNK kinase pathways as well as the NF-kappa-B pathway. The encoded protein is activated by autophosphorylation and requires magnesium as a cofactor in phosphorylating other proteins. This protein has E3 ligase activity conferred by a plant homeodomain (PHD) in its N-terminus and phospho-kinase activity conferred by a kinase domain in its C-terminus.

The MEK Kinase-1(Phospho Thr1402) Polyclonal Antibody is a highly specific and sensitive tool designed for the detection and quantification of MEK Kinase-1 protein phosphorylated at Thr1402. This antibody is produced using advanced polyclonal antibody technology, ensuring high affinity and specificity for the target protein.

MEK Kinase-1 plays a crucial role in the mitogen-activated protein kinase (MAPK) signaling pathway, which regulates various cellular processes such as cell proliferation, differentiation, and survival. Phosphorylation of MEK Kinase-1 at Thr1402 is known to activate its kinase activity, leading to downstream activation of MAPK signaling.

The MEK Kinase-1(Phospho Thr1402) Polyclonal Antibody has been rigorously validated for its performance in various applications, including Western blotting, immunohistochemistry, and immunofluorescence. It exhibits excellent sensitivity and specificity, enabling accurate and reliable detection of phosphorylated MEK Kinase-1 in complex biological samples.

This antibody is supplied as a liquid formulation, ready for immediate use. It is provided in a convenient size and concentration, allowing for easy handling and storage. The MEK Kinase-1(Phospho Thr1402) Polyclonal Antibody is suitable for both research and diagnostic purposes, making it an essential tool for scientists and clinicians studying the MAPK signaling pathway and its implications in various diseases.

In summary, the MEK Kinase-1(Phospho Thr1402) Polyclonal Antibody is a highly reliable and specific reagent for the detection and quantification of phosphorylated MEK Kinase-1. Its advanced technology, excellent performance, and versatile applications make it an indispensable tool for researchers and clinicians in the field of molecular biology and biomedical research.