MEF-2D(Phospho Ser444) Polyclonal Antibody

This gene is a member of the myocyte-specific enhancer factor 2 (MEF2) family of transcription factors. Members of this family are involved in control of muscle and neuronal cell differentiation and development, and are regulated by class II histone deacetylases. Fusions of the encoded protein with Deleted in Azoospermia-Associated Protein 1 (DAZAP1) due to a translocation have been found in an acute lymphoblastic leukemia cell line, suggesting a role in leukemogenesis. The encoded protein may also be involved in Parkinson disease and myotonic dystrophy. Alternative splicing results in multiple transcript variants.

The MEF-2D(Phospho Ser444) Polyclonal Antibody is a highly specific and sensitive tool designed for the detection and quantification of MEF-2D protein phosphorylated at Ser444. This antibody has been rigorously validated for its specificity and performance in various applications, including Western blotting, immunohistochemistry, and immunofluorescence.

MEF-2D is a transcription factor that plays a crucial role in the regulation of gene expression and cellular differentiation. Phosphorylation of MEF-2D at Ser444 has been implicated in the modulation of its transcriptional activity and downstream signaling pathways. Therefore, the ability to accurately measure the phosphorylation status of MEF-2D at Ser444 is of great importance in understanding its functional role in various biological processes.

The MEF-2D(Phospho Ser444) Polyclonal Antibody exhibits exceptional sensitivity and specificity, enabling reliable detection of phosphorylated MEF-2D protein in complex biological samples. It has been extensively validated using both recombinant and endogenous MEF-2D proteins, ensuring its reliability and reproducibility.

This antibody is produced using high-quality polyclonal antibodies that have been affinity-purified to ensure minimal cross-reactivity and maximum specificity. It has been extensively characterized and validated using various experimental approaches, including peptide blocking assays and knockout cell lines.

The MEF-2D(Phospho Ser444) Polyclonal Antibody is supplied as a liquid formulation, ready for immediate use. It is provided in a convenient size and concentration, allowing for easy and efficient experimentation. The antibody has been optimized for use in a variety of applications, including Western blotting, immunohistochemistry, and immunofluorescence, making it a versatile tool for researchers in the field of cellular and molecular biology.

In summary, the MEF-2D(Phospho Ser444) Polyclonal Antibody is a highly specific and sensitive tool for the detection and quantification of phosphorylated MEF-2D protein at Ser444. Its exceptional performance and versatility make it an invaluable asset for researchers studying the role of MEF-2D in various biological processes.