MAGD1 Polyclonal Antibody

This gene is a member of the melanoma antigen gene (MAGE) family. Most of the genes of this family encode tumor specific antigens that are not expressed in normal adult tissues except testis. Although the protein encoded by this gene shares strong homology with members of the MAGE family, it is expressed in almost all normal adult tissues. This gene has been demonstrated to be involved in the p75 neurotrophin receptor mediated programmed cell death pathway. Three transcript variants encoding two different isoforms have been found for this gene.

The MAGD1 Polyclonal Antibody is a highly specific and sensitive antibody designed for the detection of MAGD1 protein in various biological samples. This antibody is produced by immunizing rabbits with a synthetic peptide corresponding to the C-terminal region of human MAGD1 protein. The antibody has been purified using protein A affinity chromatography and is supplied as a liquid solution in phosphate-buffered saline (PBS) with 0.02% sodium azide as a preservative.

The MAGD1 Polyclonal Antibody has been extensively validated for its specificity and sensitivity in various applications, including Western blotting, immunohistochemistry, and immunofluorescence. It recognizes a single band of approximately 70 kDa in Western blot analysis of human, mouse, and rat tissue lysates. In addition, it shows strong staining of MAGD1 protein in formalin-fixed, paraffin-embedded human tissues, indicating its suitability for use in immunohistochemistry.

This antibody is an essential tool for researchers studying the function and regulation of MAGD1 protein in various biological processes, including cell proliferation, differentiation, and apoptosis. Its high specificity and sensitivity make it an ideal choice for detecting MAGD1 protein in complex biological samples, such as tissue lysates and cell extracts.

In summary, the MAGD1 Polyclonal Antibody is a reliable and high-quality antibody that provides accurate and reproducible results in various applications. Its specificity, sensitivity, and versatility make it an essential tool for researchers studying MAGD1 protein in various biological contexts.