LRP2 Polyclonal Antibody

The protein encoded by this gene, low density lipoprotein-related protein 2 (LRP2) or megalin, is a multi-ligand endocytic receptor that is expressed in many different tissues but primarily in absorptive epithilial tissues such as the kidney. This glycoprotein has a large amino-terminal extracellular domain, a single transmembrane domain, and a short carboxy-terminal cytoplasmic tail. The extracellular ligand-binding-domains bind diverse macromolecules including albumin, apolipoproteins B and E, and lipoprotein lipase. The LRP2 protein is critical for the reuptake of numerous ligands, including lipoproteins, sterols, vitamin-binding proteins, and hormones. This protein also has a role in cell-signaling; extracellular ligands include parathyroid horomones and the morphogen sonic hedgehog while cytosolic ligands include MAP kinase scaffold proteins and JNK interacting proteins. Recycling of th

The LRP4 Polyclonal Antibody is a highly specific and reliable tool designed for the detection and analysis of LRP4 protein expression in various biological samples. This antibody has been meticulously developed using advanced techniques to ensure exceptional sensitivity and specificity.

LRP4, also known as low-density lipoprotein receptor-related protein 4, plays a crucial role in various cellular processes, including synaptic development, neuromuscular junction formation, and bone metabolism. Dysregulation of LRP4 has been implicated in several diseases, making it an important target for research and diagnostic purposes.

The LRP4 Polyclonal Antibody exhibits outstanding performance in various applications, including Western blotting, immunohistochemistry, and immunofluorescence. It has been rigorously validated to provide accurate and reproducible results, enabling researchers to confidently investigate LRP4 expression and localization in different tissues and cell types.

This antibody is produced using high-quality materials and undergoes stringent quality control measures to ensure batch-to-batch consistency and reliability. It is supplied as a liquid formulation, ready for immediate use, eliminating the need for time-consuming reconstitution.

With its exceptional specificity and sensitivity, the LRP4 Polyclonal Antibody is an indispensable tool for researchers and clinicians involved in studying LRP4-related pathways and diseases. Its reliable performance and ease of use make it an ideal choice for a wide range of applications in both basic and clinical research settings.