Lck(Phospho Tyr393) Polyclonal Antibody

This gene is a member of the Src family of protein tyrosine kinases (PTKs). The encoded protein is a key signaling molecule in the selection and maturation of developing T-cells. It contains N-terminal sites for myristylation and palmitylation, a PTK domain, and SH2 and SH3 domains which are involved in mediating protein-protein interactions with phosphotyrosine-containing and proline-rich motifs, respectively. The protein localizes to the plasma membrane and pericentrosomal vesicles, and binds to cell surface receptors, including CD4 and CD8, and other signaling molecules. Multiple alternatively spliced variants encoding different isoforms have been described.

The Lck(Phospho Tyr393) Polyclonal Antibody is a highly specific and sensitive tool designed for the detection and analysis of Lck protein phosphorylated at tyrosine 393. Lck, also known as lymphocyte-specific protein tyrosine kinase, plays a crucial role in T-cell development and activation. This antibody is produced using high-quality polyclonal antibodies that have been carefully selected and validated to ensure optimal performance and reliability.

The Lck(Phospho Tyr393) Polyclonal Antibody offers exceptional specificity, enabling researchers to accurately detect and quantify the phosphorylation status of Lck at tyrosine 393. This phosphorylation event is known to regulate Lck activity and downstream signaling pathways, making it a critical target for investigation in various cellular processes.

This antibody has been extensively tested and validated in a variety of applications, including Western blotting, immunoprecipitation, and immunofluorescence. It exhibits excellent sensitivity and specificity, allowing for the detection of even low levels of phosphorylated Lck in complex biological samples.

The Lck(Phospho Tyr393) Polyclonal Antibody is supplied as a ready-to-use solution, eliminating the need for time-consuming and error-prone antibody preparation. It is provided in a convenient format, ensuring ease of use and compatibility with a wide range of experimental protocols.

With its exceptional performance and reliability, the Lck(Phospho Tyr393) Polyclonal Antibody is an invaluable tool for researchers studying Lck signaling pathways and its role in T-cell biology. Its high specificity and sensitivity make it an ideal choice for both basic research and drug discovery applications.