LAX1 Polyclonal Antibody

Negatively regulates TCR (T-cell antigen receptor)-mediated signaling in T-cells and BCR (B-cell antigen receptor)-mediated signaling in B-cells.,induction:Up-regulated in T-cells following TCR engagement.,PTM:Phosphorylated on tyrosines by Syk, Lck or ZAP70 upon TCR or BCR activation; which leads to the recruitment of GRB2, PIK3R1 and GRAP2.,subunit:When phosphorylated, interacts with GRB2, PIK3R1 and GRAP2.,tissue specificity:Expressed in spleen, thymus, and peripheral blood leukocytes. Expressed in several B-, T-, NK and monocyte cell lines.,

The LAX1 Polyclonal Antibody is a highly specific and sensitive antibody that has been developed for use in various research applications. This antibody is produced by immunizing rabbits with a synthetic peptide corresponding to the C-terminal region of the LAX1 protein. The LAX1 Polyclonal Antibody has been extensively validated for its specificity and sensitivity in Western blotting, immunohistochemistry, and immunofluorescence assays.

The LAX1 protein is a member of the LRR-RLK family of proteins and is involved in various cellular processes, including cell growth, differentiation, and development. The LAX1 Polyclonal Antibody recognizes the endogenous LAX1 protein in various tissues and cell lines, making it an ideal tool for studying the function and regulation of this protein.

The LAX1 Polyclonal Antibody is supplied as a purified IgG fraction, which has been affinity-purified using a protein A column. This antibody is provided in a liquid format and can be used directly in various applications without the need for further purification. The LAX1 Polyclonal Antibody is suitable for use in various species, including human, mouse, and rat.

In summary, the LAX1 Polyclonal Antibody is a highly specific and sensitive antibody that is ideal for studying the function and regulation of the LAX1 protein. This antibody is suitable for use in various research applications and is supplied in a purified IgG fraction, making it easy to use in various assays.