Kv10.1 Polyclonal Antibody

Voltage-gated potassium (Kv) channels represent the most complex class of voltage-gated ion channels from both functional and structural standpoints. Their diverse functions include regulating neurotransmitter release, heart rate, insulin secretion, neuronal excitability, epithelial electrolyte transport, smooth muscle contraction, and cell volume. This gene encodes a member of the potassium channel, voltage-gated, subfamily G. This member is a gamma subunit functioning as a modulatory molecule. Alternative splicing results in two transcript variants encoding distinct isoforms.

The Kv10.1 Polyclonal Antibody is a highly specific and sensitive antibody designed for the detection of Kv10.1 protein in various biological samples. This antibody is produced by immunizing rabbits with a synthetic peptide corresponding to the C-terminal region of human Kv10.1 protein. The Kv10.1 Polyclonal Antibody has been extensively validated for its specificity and sensitivity in Western blotting, immunohistochemistry, and immunofluorescence applications. It recognizes a single band of approximately 100 kDa in Western blotting and shows a strong signal in Kv10.1-expressing cells in immunohistochemistry and immunofluorescence assays. This antibody is suitable for use in various research applications, including neuroscience, cancer research, and drug discovery. It is supplied as a purified IgG fraction in phosphate-buffered saline (PBS) with 0.02% sodium azide as a preservative. The Kv10.1 Polyclonal Antibody is a reliable and high-quality tool for the detection of Kv10.1 protein and is an essential reagent for researchers studying the function and regulation of this ion channel.