KI2LA Polyclonal Antibody

Killer cell immunoglobulin-like receptors (KIRs) are transmembrane glycoproteins expressed by natural killer cells and subsets of T cells. The KIR genes are polymorphic and highly homologous and they are found in a cluster on chromosome 19q13.4 within the 1 Mb leukocyte receptor complex (LRC). The gene content of the KIR gene cluster varies among haplotypes, although several "framework" genes are found in all haplotypes (KIR3DL3, KIR3DP1, KIR3DL4, KIR3DL2). The KIR proteins are classified by the number of extracellular immunoglobulin domains (2D or 3D) and by whether they have a long (L) or short (S) cytoplasmic domain. KIR proteins with the long cytoplasmic domain transduce inhibitory signals upon ligand binding via an immune tyrosine-based inhibitory motif (ITIM), while KIR proteins with the short cytoplasmic domain lack the

The KI2LA Polyclonal Antibody is a highly specific and sensitive immunological tool designed for the detection and quantification of KI2LA protein in various biological samples. This antibody is produced by immunizing rabbits with a synthetic peptide corresponding to a unique epitope of the KI2LA protein.

The KI2LA Polyclonal Antibody exhibits exceptional affinity and selectivity towards the target protein, ensuring accurate and reliable results in a wide range of applications, including Western blotting, immunohistochemistry, and enzyme-linked immunosorbent assays (ELISA).

With its superior sensitivity, this antibody allows for the detection of even low levels of KI2LA protein, making it an invaluable tool for researchers studying the expression and function of this protein in various biological systems.

Furthermore, the KI2LA Polyclonal Antibody has been rigorously tested for cross-reactivity with other proteins to ensure specificity and minimize any potential interference.

This product is supplied as a liquid formulation, ready for immediate use, and is available in various sizes to accommodate different experimental needs. Each batch of the KI2LA Polyclonal Antibody undergoes stringent quality control measures to guarantee consistent performance and reproducibility.

In summary, the KI2LA Polyclonal Antibody is a reliable and efficient tool for the detection and quantification of KI2LA protein, offering researchers a valuable resource for their studies in various fields, including molecular biology, biochemistry, and biomedical research.