KDM5B Polyclonal Antibody

This gene encodes a lysine-specific histone demethylase that belongs to the jumonji/ARID domain-containing family of histone demethylases. The encoded protein is capable of demethylating tri-, di- and monomethylated lysine 4 of histone H3. This protein plays a role in the transcriptional repression or certain tumor suppressor genes and is upregulated in certain cancer cells. This protein may also play a role in genome stability and DNA repair. Alternate splicing resultsi n multiple transcript variants.

The KDM5B Polyclonal Antibody is a highly specific and sensitive tool designed for the detection and analysis of KDM5B protein expression in various biological samples. This antibody is produced using advanced immunization techniques, ensuring high affinity and specificity towards the target protein.

KDM5B, also known as JARID1B, is a histone demethylase that plays a crucial role in gene regulation and chromatin remodeling. It is involved in the removal of methyl groups from histone H3 lysine 4 (H3K4), leading to transcriptional repression of target genes. Dysregulation of KDM5B has been implicated in various diseases, including cancer, making it an important target for research and therapeutic development.

The KDM5B Polyclonal Antibody has been extensively validated for its performance in various applications, including Western blotting, immunohistochemistry, and immunofluorescence. It exhibits excellent sensitivity and specificity, enabling accurate and reliable detection of KDM5B protein expression in both cell lysates and tissue sections.

This antibody is supplied as a liquid formulation, ready to use for immediate application. It is provided in a convenient size, allowing for multiple experiments without the need for frequent reordering. The KDM5B Polyclonal Antibody is manufactured under strict quality control standards, ensuring consistent and reproducible results.

In summary, the KDM5B Polyclonal Antibody is a valuable tool for researchers studying the role of KDM5B in gene regulation and disease. Its high specificity, sensitivity, and versatility make it an ideal choice for various applications, facilitating accurate and reliable analysis of KDM5B protein expression.