KCNN1 Polyclonal Antibody

Action potentials in vertebrate neurons are followed by an afterhyperpolarization (AHP) that may persist for several seconds and may have profound consequences for the firing pattern of the neuron. Each component of the AHP is kinetically distinct and is mediated by different calcium-activated potassium channels. The protein encoded by this gene is activated before membrane hyperpolarization and is thought to regulate neuronal excitability by contributing to the slow component of synaptic AHP. The encoded protein is an integral membrane protein that forms a voltage-independent calcium-activated channel with three other calmodulin-binding subunits. This gene is a member of the KCNN family of potassium channel genes.

The Keratin 77 Polyclonal Antibody is a highly specific and sensitive tool designed for the detection and analysis of Keratin 77 protein expression. This antibody is produced using advanced techniques and rigorous quality control measures to ensure optimal performance and reliability.

Keratin 77 is a member of the keratin family, which plays a crucial role in maintaining the structural integrity and function of epithelial cells. It is predominantly expressed in the hair follicles, nails, and other epithelial tissues. Aberrant expression of Keratin 77 has been implicated in various pathological conditions, including skin disorders and certain types of cancer.

The Keratin 77 Polyclonal Antibody exhibits exceptional specificity, binding exclusively to the target protein with minimal cross-reactivity to other keratin isoforms. It has been extensively validated in various experimental settings, including Western blotting, immunohistochemistry, and immunofluorescence. This antibody consistently delivers robust and reliable results, enabling accurate and precise detection of Keratin 77 expression.

With its high sensitivity, the Keratin 77 Polyclonal Antibody allows for the detection of low levels of the target protein, making it an ideal choice for both qualitative and quantitative analysis. Its superior performance and versatility make it suitable for a wide range of research applications, including basic research, drug discovery, and diagnostic development.

The Keratin 77 Polyclonal Antibody is supplied as a liquid formulation, ensuring ease of use and convenience. It is provided in a ready-to-use format, eliminating the need for time-consuming and error-prone antibody preparation. The antibody is also available in various sizes to accommodate different experimental requirements.

In summary, the Keratin 77 Polyclonal Antibody is a highly reliable and specific tool for the detection and analysis of Keratin 77 protein expression. Its exceptional performance, sensitivity, and versatility make it an invaluable asset for researchers and clinicians alike in their pursuit of understanding the role of Keratin 77 in various biological processes and diseases.