JAK2(Phospho Tyr221) Polyclonal Antibody

This gene product is a protein tyrosine kinase involved in a specific subset of cytokine receptor signaling pathways. It has been found to be constituitively associated with the prolactin receptor and is required for responses to gamma interferon. Mice that do not express an active protein for this gene exhibit embryonic lethality associated with the absence of definitive erythropoiesis.

The JAK2(Phospho Tyr221) Polyclonal Antibody is a highly specific and sensitive tool designed for the detection and quantification of JAK2 protein phosphorylated at tyrosine 221. This antibody is produced using advanced polyclonal antibody technology, ensuring high affinity and specificity for the target protein.

The JAK2 protein plays a crucial role in various cellular processes, including cell growth, differentiation, and survival. Phosphorylation of JAK2 at tyrosine 221 is known to regulate its activity and downstream signaling pathways. Therefore, the ability to accurately measure the phosphorylation status of JAK2 is essential for understanding its functional role in cellular processes and disease development.

This polyclonal antibody has been rigorously validated for its specificity and sensitivity through various experimental approaches, including Western blotting, immunoprecipitation, and immunofluorescence. It exhibits minimal cross-reactivity with other proteins, ensuring reliable and accurate results.

The JAK2(Phospho Tyr221) Polyclonal Antibody is supplied as a liquid formulation, ready for immediate use in various applications, including research studies, drug development, and diagnostic assays. It is compatible with multiple detection methods, such as chemiluminescence, fluorescence, and colorimetric assays.

With its high specificity, sensitivity, and versatility, the JAK2(Phospho Tyr221) Polyclonal Antibody is an indispensable tool for researchers and scientists working in the field of cellular signaling and disease biology. Its reliable performance and consistent results make it an ideal choice for studying the role of JAK2 phosphorylation in various physiological and pathological conditions.