IκB-alpha(Phospho Tyr305) Polyclonal Antibody

This gene encodes a member of the NF-kappa-B inhibitor family, which contain multiple ankrin repeat domains. The encoded protein interacts with REL dimers to inhibit NF-kappa-B/REL complexes which are involved in inflammatory responses. The encoded protein moves between the cytoplasm and the nucleus via a nuclear localization signal and CRM1-mediated nuclear export. Mutations in this gene have been found in ectodermal dysplasia anhidrotic with T-cell immunodeficiency autosomal dominant disease.

The IκB-alpha(Phospho Tyr305) Polyclonal Antibody is a highly specific and sensitive tool designed for the detection and quantification of IκB-alpha protein phosphorylated at Tyr305. This antibody is produced using advanced polyclonal antibody technology, ensuring high affinity and specificity for the target protein.

IκB-alpha is a crucial regulator of the nuclear factor kappa B (NF-κB) signaling pathway, which plays a pivotal role in various cellular processes, including inflammation, immune response, and cell survival. Phosphorylation of IκB-alpha at Tyr305 is known to modulate its function and stability, thereby influencing NF-κB activation.

The IκB-alpha(Phospho Tyr305) Polyclonal Antibody has been rigorously validated for its performance in various applications, including Western blotting, immunohistochemistry, and immunofluorescence. It exhibits exceptional sensitivity and specificity, enabling accurate and reliable detection of phosphorylated IκB-alpha in complex biological samples.

This antibody is supplied as a liquid formulation, ready for immediate use. It is provided in a convenient size, ensuring cost-effectiveness and minimizing wastage. The IκB-alpha(Phospho Tyr305) Polyclonal Antibody is compatible with a wide range of experimental conditions and can be used in diverse research areas, such as cancer biology, immunology, and signal transduction.

With its exceptional performance and versatility, the IκB-alpha(Phospho Tyr305) Polyclonal Antibody is an indispensable tool for researchers aiming to investigate the role of IκB-alpha phosphorylation in various biological processes. Trust in its reliability and accuracy to advance your scientific discoveries.