ITSN2 Polyclonal Antibody

This gene encodes a cytoplasmic protein which contains SH3 domains. This protein is a member of a family of proteins involved in clathrin-mediated endocytosis. Intersectin 2 is thought to regulate the formation of clathrin-coated vesicles and also may function in the induction of T cell antigen receptor (TCR) endocytosis. Alternatively spliced transcript variants have been found for this gene that encode three distinct isoforms. Additional variants have been found but their full length nature has not been determined.

The ITSN2 Polyclonal Antibody is a highly specific and reliable tool for the detection and analysis of Intersectin 2 (ITSN2) protein in various biological samples. This antibody has been extensively validated for its superior performance in immunohistochemistry (IHC), immunofluorescence (IF), and western blotting (WB) applications.

ITSN2 is a key regulator of endocytosis and vesicle trafficking, playing a crucial role in various cellular processes such as receptor internalization, membrane remodeling, and signal transduction. Dysregulation of ITSN2 has been implicated in several pathological conditions, including cancer, neurodegenerative disorders, and cardiovascular diseases.

The ITSN2 Polyclonal Antibody has been developed using high-quality immunogens and advanced immunization techniques, ensuring its exceptional specificity and sensitivity. It exhibits minimal cross-reactivity with other related proteins, enabling accurate and reliable detection of ITSN2 in complex biological samples.

This antibody demonstrates excellent performance in IHC, allowing for precise localization and visualization of ITSN2 in tissue sections. It also exhibits strong and specific staining in IF, enabling detailed examination of ITSN2 distribution and co-localization with other cellular markers. Additionally, the ITSN2 Polyclonal Antibody shows robust and specific band detection in WB, facilitating the quantification and analysis of ITSN2 protein expression levels.

The ITSN2 Polyclonal Antibody is supplied as a ready-to-use solution, eliminating the need for time-consuming and error-prone antibody preparation. It is available in various sizes to accommodate different experimental requirements. Each batch of this antibody undergoes rigorous quality control procedures to ensure consistent and reliable performance.

In summary, the ITSN2 Polyclonal Antibody is a highly specific and reliable tool for the detection and analysis of ITSN2 protein. Its exceptional performance in IHC, IF, and WB applications, along with its superior specificity and sensitivity, make it an invaluable asset for researchers studying the role of ITSN2 in various biological processes and diseases.