ITBP2 Polyclonal Antibody

The tail domain binds to the cytoplasmic domain of both integrin beta-1a and beta-1d isoforms. The presence of Ca(2+) ions does not prevent binding of a fragment consisting of the second cysteine rich repeat and the tail domain but prevents the binding of the full-length protein.,May play a role during maturation and/or organization of muscles cells.,Contains 1 CS domain.,Contains 2 CHORD domains.,subunit:Interacts with beta-1 integrin subunit. This interaction is regulated by divalent cations, and it occurs only in absence of calcium.,tissue specificity:Expressed in skeletal and cardiac muscles but not in other tissues.,

The ITBP2 Polyclonal Antibody is a highly specific and reliable tool for the detection and analysis of ITBP2 protein expression in various biological samples. This antibody has been extensively validated for its superior performance in immunohistochemistry (IHC), immunofluorescence (IF), and western blotting (WB) applications.

ITBP2, also known as Interferon-induced protein with tetratricopeptide repeats 2, is a crucial component of the interferon signaling pathway. It plays a vital role in the regulation of immune responses and cellular antiviral defense mechanisms. Dysregulation of ITBP2 expression has been implicated in various diseases, including viral infections and autoimmune disorders.

The ITBP2 Polyclonal Antibody has been meticulously developed using high-quality immunogens and advanced immunization techniques. It exhibits exceptional specificity towards ITBP2, ensuring minimal cross-reactivity with other proteins. This antibody offers excellent sensitivity, enabling the detection of low-abundance ITBP2 protein levels in complex biological samples.

In IHC applications, the ITBP2 Polyclonal Antibody provides clear and distinct staining patterns, allowing for precise localization and visualization of ITBP2 protein expression in tissue sections. In IF assays, it produces bright and specific signals, facilitating the examination of ITBP2 distribution within cells. Additionally, in WB experiments, this antibody reliably detects the presence of ITBP2 protein bands at the expected molecular weight.

The ITBP2 Polyclonal Antibody is supplied as a ready-to-use solution, ensuring convenience and ease of use. It is compatible with a wide range of experimental conditions and can be employed in various research areas, including immunology, virology, and molecular biology. With its exceptional performance and reliability, this antibody is an indispensable tool for scientists and researchers studying the role of ITBP2 in health and disease.

Note: For optimal results, it is recommended to follow the provided protocols and guidelines for sample preparation, antibody dilution, and detection methods.