IRF-3(Phospho Ser396) Polyclonal Antibody

This gene encodes a member of the interferon regulatory transcription factor (IRF) family. The encoded protein is found in an inactive cytoplasmic form that upon serine/threonine phosphorylation forms a complex with CREBBP. This complex translocates to the nucleus and activates the transcription of interferons alpha and beta, as well as other interferon-induced genes. Alternatively spliced transcript variants encoding multiple isoforms have been observed for this gene.

The IRF-3(Phospho Ser396) Polyclonal Antibody is a highly specific and sensitive tool designed for the detection and analysis of phosphorylated serine 396 residue of the interferon regulatory factor 3 (IRF-3) protein. This antibody is produced using advanced polyclonal antibody technology, ensuring high affinity and specificity towards the target epitope.

IRF-3 is a crucial transcription factor involved in the regulation of innate immune responses, particularly in the production of type I interferons. Phosphorylation of serine 396 residue is a key post-translational modification that activates IRF-3, leading to its nuclear translocation and subsequent induction of interferon-stimulated genes.

The IRF-3(Phospho Ser396) Polyclonal Antibody has been extensively validated for its performance in various applications, including Western blotting, immunoprecipitation, immunofluorescence, and immunohistochemistry. It exhibits exceptional sensitivity and specificity, enabling accurate and reliable detection of phosphorylated IRF-3 in various sample types.

This antibody is supplied as a liquid formulation, ready for immediate use. It is provided in a convenient size and concentration, ensuring cost-effectiveness and minimizing wastage. The product is rigorously quality-controlled to ensure consistent and reproducible results, batch after batch.

Researchers and scientists studying the intricate mechanisms of innate immune responses and the role of IRF-3 in viral infections, autoimmune diseases, and cancer will greatly benefit from the IRF-3(Phospho Ser396) Polyclonal Antibody. Its exceptional performance and reliability make it an indispensable tool for elucidating the complex signaling pathways involved in immune regulation.

In summary, the IRF-3(Phospho Ser396) Polyclonal Antibody is a highly specific and sensitive reagent that enables accurate detection and analysis of phosphorylated IRF-3. Its exceptional performance, reliability, and versatility make it an invaluable tool for researchers in the field of immunology and molecular biology.