IRF-3(Phospho Ser385) Polyclonal Antibody

This gene encodes a member of the interferon regulatory transcription factor (IRF) family. The encoded protein is found in an inactive cytoplasmic form that upon serine/threonine phosphorylation forms a complex with CREBBP. This complex translocates to the nucleus and activates the transcription of interferons alpha and beta, as well as other interferon-induced genes. Alternatively spliced transcript variants encoding multiple isoforms have been observed for this gene.

The IRF-3(Phospho Ser385) Polyclonal Antibody is a highly specific and sensitive tool designed for the detection and analysis of IRF-3 protein phosphorylated at Serine 385. This antibody is produced using advanced polyclonal antibody technology, ensuring high affinity and specificity for the target protein.

IRF-3, also known as interferon regulatory factor 3, plays a crucial role in the innate immune response by regulating the expression of interferon genes. Phosphorylation of IRF-3 at Serine 385 is a key post-translational modification that activates its transcriptional activity and enhances its ability to induce interferon production.

The IRF-3(Phospho Ser385) Polyclonal Antibody has been extensively validated for its performance in various applications, including Western blotting, immunohistochemistry, and immunofluorescence. It exhibits excellent sensitivity and specificity, enabling accurate and reliable detection of phosphorylated IRF-3 in various sample types.

This antibody is supplied as a liquid formulation, ready for immediate use. It is provided in a convenient size and concentration, ensuring cost-effectiveness and minimizing waste. The product is stored at -20°C, ensuring long-term stability and preserving its activity.

In summary, the IRF-3(Phospho Ser385) Polyclonal Antibody is a valuable tool for researchers studying the role of IRF-3 phosphorylation in the innate immune response. Its high specificity, sensitivity, and versatility make it an essential component of any laboratory involved in immunological research.