Intestinal Cell Kinase(Phospho Tyr159) Polyclonal Antibody

Eukaryotic protein kinases are enzymes that belong to a very extensive family of proteins which share a conserved catalytic core common with both serine/threonine and tyrosine protein kinases. This gene encodes an intestinal serine/threonine kinase harboring a dual phosphorylation site found in mitogen-activating protein (MAP) kinases. The protein localizes to the intestinal crypt region and is thought to be important in intestinal epithelial cell proliferation and differentiation. Alternative splicing has been observed at this locus and two variants, encoding the same isoform, have been identified.

The Intestinal Cell Kinase (Phospho Tyr159) Polyclonal Antibody is a highly specific and sensitive tool designed for the detection and analysis of Intestinal Cell Kinase (ICK) protein phosphorylated at tyrosine 159 residue. This antibody is produced through a rigorous process of immunization and purification, ensuring high affinity and specificity towards the target protein.

Intestinal Cell Kinase (ICK) is a serine/threonine protein kinase that plays a crucial role in various cellular processes, including cell proliferation, differentiation, and survival. Phosphorylation of ICK at tyrosine 159 residue has been implicated in the regulation of its enzymatic activity and downstream signaling pathways.

The Polyclonal Antibody is derived from a host animal that has been immunized with a synthetic phospho-peptide corresponding to the phosphorylated tyrosine 159 residue of ICK protein. The antibody has been extensively validated for its specificity and sensitivity through various experimental techniques, including Western blotting, immunoprecipitation, and immunofluorescence.

This antibody exhibits exceptional performance in detecting endogenous levels of phosphorylated ICK protein in various cell lysates and tissue samples. It demonstrates minimal cross-reactivity with non-phosphorylated ICK protein and other related kinases, ensuring accurate and reliable results.

The Intestinal Cell Kinase (Phospho Tyr159) Polyclonal Antibody is supplied as a liquid formulation in a convenient size of 100 µg. It is provided in a ready-to-use format, eliminating the need for additional reagents or preparations. The antibody is suitable for use in various applications, including but not limited to Western blotting, immunoprecipitation, immunofluorescence, and immunohistochemistry.

In summary, the Intestinal Cell Kinase (Phospho Tyr159) Polyclonal Antibody is a highly specific and sensitive tool that enables the detection and analysis of phosphorylated ICK protein. Its exceptional performance, reliability, and convenience make it an ideal choice for researchers and scientists studying the role of ICK in cellular processes and signaling pathways.