Integrin alphaD Polyclonal Antibody

This gene belongs to the beta-2 integrin family of membrane glycoproteins, which are are composed of non-covalently linked alpha and beta subunits to form a heterodimer. It encodes the alpha subunit of the cell surface heterodimers and is involved in the activation and adhesion functions of leukocytes. The gene is located about 11kb downstream of the integrin subunit alpha X gene, another member of the integrin family. It is expressed in the tissue and circulating myeloid leukocytes. Alternative splicing results in multiple transcript variants.

The Integrin alphaD Polyclonal Antibody is a highly specific and reliable tool for the detection and analysis of Integrin alphaD protein expression in various biological samples. This antibody has been extensively validated for its exceptional performance in immunohistochemistry (IHC), immunofluorescence (IF), and western blotting (WB) applications.

Integrin alphaD is a cell surface receptor that plays a crucial role in cell adhesion and migration processes. It is primarily expressed on leukocytes, particularly on monocytes, macrophages, and dendritic cells. The Integrin alphaD Polyclonal Antibody specifically recognizes the extracellular domain of Integrin alphaD and exhibits minimal cross-reactivity with other integrin family members.

This antibody is produced using high-quality polyclonal antibodies generated in rabbits immunized with a synthetic peptide corresponding to a specific region of the Integrin alphaD protein. The resulting antibody exhibits high affinity and specificity, ensuring accurate and reliable detection of Integrin alphaD in various experimental settings.

The Integrin alphaD Polyclonal Antibody is supplied as a liquid formulation in a convenient size of 100 µg. It is provided in a ready-to-use format, eliminating the need for any additional preparation steps. The antibody is optimized for use in a wide range of applications, including IHC, IF, and WB, making it suitable for diverse research purposes.

In summary, the Integrin alphaD Polyclonal Antibody is a valuable tool for researchers studying cell adhesion and migration processes, particularly in the context of leukocyte biology. Its high specificity, reliability, and versatility make it an essential component of any laboratory involved in the investigation of Integrin alphaD protein expression.