Insulin R(Phospho Tyr1355) Polyclonal Antibody

This gene encodes a member of the receptor tyrosine kinase family of proteins. The encoded preproprotein is proteolytically processed to generate alpha and beta subunits that form a heterotetrameric receptor. Binding of insulin or other ligands to this receptor activates the insulin signaling pathway, which regulates glucose uptake and release, as well as the synthesis and storage of carbohydrates, lipids and protein. Mutations in this gene underlie the inherited severe insulin resistance syndromes including type A insulin resistance syndrome, Donohue syndrome and Rabson-Mendenhall syndrome. Alternative splicing results in multiple transcript variants.

The Insulin R(Phospho Tyr1355) Polyclonal Antibody is a highly specific and sensitive tool designed for the detection and quantification of insulin receptor phosphorylated at tyrosine 1355. This antibody is produced using advanced techniques to ensure high affinity and specificity, making it an ideal choice for various applications in research and diagnostics.

The Insulin R(Phospho Tyr1355) Polyclonal Antibody exhibits exceptional performance in immunohistochemistry, immunofluorescence, and Western blotting assays. It recognizes the phosphorylated form of the insulin receptor at tyrosine 1355 with remarkable sensitivity, enabling accurate and reliable detection of this critical post-translational modification.

This antibody is meticulously validated to ensure consistent and reproducible results. It has been extensively tested against a wide range of samples, including human, mouse, and rat tissues, to guarantee its broad applicability and reliability. Furthermore, it exhibits minimal cross-reactivity with non-phosphorylated insulin receptor and other related proteins, ensuring specific and precise detection.

The Insulin R(Phospho Tyr1355) Polyclonal Antibody is supplied in a convenient and ready-to-use format, allowing for easy integration into various experimental protocols. It is provided in a liquid formulation, ensuring stability and ease of use. The antibody is also available in different sizes to accommodate different experimental needs.

In summary, the Insulin R(Phospho Tyr1355) Polyclonal Antibody is a highly reliable and specific tool for the detection and quantification of insulin receptor phosphorylated at tyrosine 1355. Its exceptional performance, broad applicability, and meticulous validation make it an indispensable asset for researchers and diagnosticians in the field of insulin signaling and related studies.