INP5E Polyclonal Antibody

The protein encoded by this gene is an inositol 1,4,5-trisphosphate (InsP3) 5-phosphatase. InsP3 5-phosphatases hydrolyze Ins(1,4,5)P3, which mobilizes intracellular calcium and acts as a second messenger mediating cell responses to various stimulation. Studies of the mouse counterpart suggest that this protein may hydrolyze phosphatidylinositol 3,4,5-trisphosphate and phosphatidylinositol 3,5-bisphosphate on the cytoplasmic Golgi membrane and thereby regulate Golgi-vesicular trafficking. Mutations in this gene cause Joubert syndrome; a clinically and genetically heterogenous group of disorders characterized by midbrain-hindbrain malformation and various associated ciliopathies that include retinal dystrophy, nephronophthisis, liver fibrosis and polydactyly. Alternative splicing results in multiple transcript variants encoding different isoforms.

The INP5E Polyclonal Antibody is a highly specific and reliable tool for the detection and analysis of INP5E protein expression in various biological samples. This antibody has been meticulously developed and validated to ensure exceptional performance and accuracy in a wide range of applications, including Western blotting, immunohistochemistry, and immunofluorescence.

The INP5E Polyclonal Antibody exhibits exceptional sensitivity and specificity, enabling the precise identification and quantification of INP5E protein levels in both normal and diseased tissues. Its high affinity for the target protein ensures minimal background noise and reliable results, even in complex biological matrices.

This antibody has been rigorously tested and validated using a variety of experimental approaches, guaranteeing its reliability and reproducibility. Its exceptional performance characteristics make it an ideal choice for researchers and scientists working in the fields of cell biology, molecular biology, and biochemistry.

The INP5E Polyclonal Antibody is supplied as a ready-to-use solution, eliminating the need for time-consuming and error-prone antibody preparation. Its user-friendly format allows for easy and convenient handling, saving valuable time and resources in the laboratory.

With its exceptional performance, reliability, and ease of use, the INP5E Polyclonal Antibody is an indispensable tool for researchers seeking to unravel the intricate mechanisms underlying INP5E protein function and its role in various biological processes. Trust in its superior quality and performance to advance your research and contribute to scientific discoveries.