ING3 Polyclonal Antibody

The protein encoded by this gene is similar to ING1, a tumor suppressor protein that can interact with TP53, inhibit cell growth, and induce apoptosis. This protein contains a PHD-finger, which is a common motif in proteins involved in chromatin remodeling. This gene can activate p53 trans-activated promoters, including promoters of p21/waf1 and bax. Overexpression of this gene has been shown to inhibit cell growth and induce apoptosis. Allelic loss and reduced expression of this gene were detected in head and neck cancers. Two alternatively spliced transcript variants encoding different isoforms have been observed.

The ING3 Polyclonal Antibody is a highly specific and reliable tool for the detection and analysis of ING3 protein expression in various biological samples. This antibody has been meticulously developed and validated to ensure optimal performance and accuracy in a wide range of applications, including Western blotting, immunohistochemistry, and immunofluorescence.

The ING3 Polyclonal Antibody exhibits exceptional sensitivity and specificity, enabling the precise identification and quantification of ING3 protein levels in both normal and diseased tissues. Its superior affinity and selectivity for ING3 make it an invaluable asset for researchers and scientists studying the role of this protein in various cellular processes, such as DNA repair, apoptosis, and cell cycle regulation.

This antibody has been rigorously tested and validated to ensure consistent and reproducible results. Its high-quality formulation guarantees minimal background noise and maximum signal intensity, allowing for accurate and reliable data interpretation. Furthermore, the ING3 Polyclonal Antibody demonstrates excellent cross-reactivity with a wide range of species, making it suitable for use in diverse experimental settings.

The ING3 Polyclonal Antibody is supplied in a convenient and user-friendly format, ensuring ease of use and storage. It is provided in a liquid form, ready for immediate use, eliminating the need for time-consuming reconstitution procedures. The antibody is also stable and long-lasting, maintaining its performance and integrity even after prolonged storage.

In summary, the ING3 Polyclonal Antibody is a highly specific, sensitive, and reliable tool for the detection and analysis of ING3 protein expression. Its exceptional performance, versatility, and ease of use make it an indispensable resource for researchers and scientists in the field of molecular biology and beyond.