IL-8R beta(Phospho Ser347) Polyclonal Antibody

The protein encoded by this gene is a member of the G-protein-coupled receptor family. This protein is a receptor for interleukin 8 (IL8). It binds to IL8 with high affinity, and transduces the signal through a G-protein activated second messenger system. This receptor also binds to chemokine (C-X-C motif) ligand 1 (CXCL1/MGSA), a protein with melanoma growth stimulating activity, and has been shown to be a major component required for serum-dependent melanoma cell growth. This receptor mediates neutrophil migration to sites of inflammation. The angiogenic effects of IL8 in intestinal microvascular endothelial cells are found to be mediated by this receptor. Knockout studies in mice suggested that this receptor controls the positioning of oligodendrocyte precursors in developing spinal cord by arresting their migration. This gene, IL8RA, a gene encoding another high affinity IL8 receptor, as

The IL-8R beta(Phospho Ser347) Polyclonal Antibody is a highly specific and sensitive tool designed for the detection and quantification of IL-8R beta protein phosphorylated at Ser347. This antibody is produced using advanced polyclonal antibody technology, ensuring high affinity and specificity towards the target protein.

IL-8R beta, also known as interleukin-8 receptor beta, plays a crucial role in mediating the biological effects of interleukin-8 (IL-8), a chemokine involved in various inflammatory processes. Phosphorylation of IL-8R beta at Ser347 has been implicated in the regulation of downstream signaling pathways and cellular responses.

The IL-8R beta(Phospho Ser347) Polyclonal Antibody has been rigorously validated for its performance in various applications, including Western blotting, immunohistochemistry, and immunofluorescence. It exhibits exceptional sensitivity and specificity, enabling accurate and reliable detection of phosphorylated IL-8R beta protein in complex biological samples.

This antibody is manufactured using high-quality materials and state-of-the-art techniques, ensuring batch-to-batch consistency and reproducibility. It is supplied as a liquid formulation, ready for immediate use without the need for additional reagents or preparations.

Researchers and scientists in the fields of immunology, cell biology, and inflammation will greatly benefit from the IL-8R beta(Phospho Ser347) Polyclonal Antibody, as it provides a valuable tool for studying the phosphorylation status and functional implications of IL-8R beta in various biological systems.

In summary, the IL-8R beta(Phospho Ser347) Polyclonal Antibody is a reliable and efficient reagent for the detection and quantification of phosphorylated IL-8R beta protein. Its high specificity, sensitivity, and versatility make it an indispensable tool for elucidating the role of IL-8R beta phosphorylation in cellular processes and disease mechanisms.