BT Lab
SKU:BT-AP10349
IL-7R(Phospho Tyr449) Polyclonal Antibody
IL-7R(Phospho Tyr449) Polyclonal Antibody
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The protein encoded by this gene is a receptor for interleukin 7 (IL7). The function of this receptor requires the interleukin 2 receptor, gamma chain (IL2RG), which is a common gamma chain shared by the receptors of various cytokines, including interleukins 2, 4, 7, 9, and 15. This protein has been shown to play a critical role in V(D)J recombination during lymphocyte development. Defects in this gene may be associated with severe combined immunodeficiency (SCID). Alternatively spliced transcript variants have been found.
The IL-7R(Phospho Tyr449) Polyclonal Antibody is a highly specific and sensitive tool designed for the detection and quantification of IL-7R phosphorylated at Tyr449. This antibody is produced using advanced techniques in polyclonal antibody development, ensuring high affinity and specificity for the target antigen.
IL-7R, also known as interleukin-7 receptor, plays a crucial role in the regulation of immune cell development and function. Phosphorylation of Tyr449 residue in IL-7R is known to be involved in signal transduction pathways that control cell proliferation, survival, and differentiation. Therefore, the detection and analysis of IL-7R phosphorylation at Tyr449 is of great importance in understanding the molecular mechanisms underlying immune responses.
The IL-7R(Phospho Tyr449) Polyclonal Antibody has been extensively validated for its performance in various applications, including Western blotting, immunoprecipitation, and immunofluorescence. It exhibits exceptional sensitivity and specificity, enabling accurate and reliable detection of IL-7R phosphorylation at Tyr449 in a wide range of sample types.
This antibody is produced using high-quality materials and rigorous quality control measures to ensure batch-to-batch consistency and reproducibility. It is supplied as a liquid formulation in a convenient size, allowing for easy handling and storage.
In summary, the IL-7R(Phospho Tyr449) Polyclonal Antibody is a valuable tool for researchers studying IL-7R signaling pathways and its role in immune regulation. Its high specificity, sensitivity, and versatility make it an ideal choice for various experimental applications.
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