IL-1RI(Phospho Tyr496) Polyclonal Antibody

This gene encodes a cytokine receptor that belongs to the interleukin-1 receptor family. The encoded protein is a receptor for interleukin-1 alpha, interleukin-1 beta, and interleukin-1 receptor antagonist. It is an important mediator involved in many cytokine-induced immune and inflammatory responses. This gene is located in a cluster of related cytokine receptor genes on chromosome 2q12.

The IL-1RI(Phospho Tyr496) Polyclonal Antibody is a highly specific and sensitive tool designed for the detection and quantification of IL-1RI protein phosphorylated at tyrosine 496. This antibody has been meticulously developed and rigorously validated to ensure optimal performance in various applications, including Western blotting, immunoprecipitation, and immunofluorescence.

IL-1RI, also known as Interleukin-1 receptor type 1, plays a crucial role in mediating the biological effects of IL-1 cytokines. Phosphorylation of tyrosine 496 in IL-1RI has been implicated in the regulation of downstream signaling pathways, making it an important target for research in the field of immunology and inflammation.

The IL-1RI(Phospho Tyr496) Polyclonal Antibody exhibits exceptional specificity, recognizing only the phosphorylated form of IL-1RI at tyrosine 496. This ensures accurate and reliable results, minimizing any potential cross-reactivity with non-phosphorylated forms of the protein. Additionally, the antibody demonstrates high sensitivity, enabling the detection of low levels of phosphorylated IL-1RI in complex biological samples.

This antibody has been extensively validated using various experimental approaches, including siRNA knockdown, overexpression, and peptide blocking assays. These validations confirm the specificity and reliability of the IL-1RI(Phospho Tyr496) Polyclonal Antibody, ensuring its suitability for a wide range of research applications.

Furthermore, the IL-1RI(Phospho Tyr496) Polyclonal Antibody has been manufactured using state-of-the-art techniques and quality control processes. Each batch is subjected to rigorous testing to ensure consistent performance and lot-to-lot reproducibility. This guarantees the reliability and accuracy of the antibody, providing researchers with confidence in their experimental results.

In summary, the IL-1RI(Phospho Tyr496) Polyclonal Antibody is a highly specific and sensitive tool for the detection and quantification of phosphorylated IL-1RI at tyrosine 496. With its exceptional performance, extensive validation, and stringent quality control, this antibody is an invaluable asset for researchers studying the role of IL-1RI phosphorylation in immunology and inflammation.