IL-17C Polyclonal Antibody

The protein encoded by this gene is a T cell-derived cytokine that shares the sequence similarity with IL17. This cytokine was reported to stimulate the release of tumor necrosis factor alpha and interleukin 1 beta from a monocytic cell line. The expression of this cytokine was found to be restricted to activated T cells.

The IL-17C Polyclonal Antibody is a highly specific and sensitive tool for the detection and quantification of interleukin-17C (IL-17C) in various biological samples. This antibody is produced by immunizing rabbits with a synthetic peptide corresponding to the C-terminal region of human IL-17C protein. The resulting polyclonal antibody has been purified using protein A affinity chromatography and validated for its specificity and sensitivity in various immunoassays.

IL-17C is a member of the interleukin-17 (IL-17) family of cytokines, which play important roles in the regulation of immune responses and inflammation. IL-17C is produced by various cell types, including epithelial cells, and has been implicated in the pathogenesis of various inflammatory and autoimmune diseases. The IL-17C Polyclonal Antibody can be used to study the expression and function of IL-17C in various biological systems, including cell cultures, animal models, and human tissues.

The IL-17C Polyclonal Antibody is supplied as a liquid in phosphate-buffered saline (PBS) containing 0.02% sodium azide as a preservative. The antibody is suitable for use in various immunoassays, including Western blotting, immunohistochemistry, and ELISA. The recommended working dilution for Western blotting is 1:500-1:1000, while for immunohistochemistry and ELISA, the optimal dilution should be determined by the user.

In summary, the IL-17C Polyclonal Antibody is a reliable and versatile tool for the detection and quantification of IL-17C in various biological samples. Its high specificity and sensitivity make it an ideal reagent for researchers studying the role of IL-17C in immune responses and inflammation.