ICAD Polyclonal Antibody

Apoptosis is a cell death process that removes toxic and/or useless cells during mammalian development. The apoptotic process is accompanied by shrinkage and fragmentation of the cells and nuclei and degradation of the chromosomal DNA into nucleosomal units. DNA fragmentation factor (DFF) is a heterodimeric protein of 40-kD (DFFB) and 45-kD (DFFA) subunits. DFFA is the substrate for caspase-3 and triggers DNA fragmentation during apoptosis. DFF becomes activated when DFFA is cleaved by caspase-3. The cleaved fragments of DFFA dissociate from DFFB, the active component of DFF. DFFB has been found to trigger both DNA fragmentation and chromatin condensation during apoptosis. Two alternatively spliced transcript variants encoding distinct isoforms have been found for this gene.

The ICAD Polyclonal Antibody is a highly specific and reliable tool designed for the detection and quantification of ICAD protein in various biological samples. This antibody has been meticulously developed using advanced techniques to ensure exceptional performance and accuracy.

The ICAD Polyclonal Antibody exhibits a high affinity towards its target protein, ICAD, enabling precise and sensitive detection. It has been extensively validated for use in various applications, including Western blotting, immunohistochemistry, and immunofluorescence.

This antibody is produced using state-of-the-art recombinant DNA technology, ensuring batch-to-batch consistency and minimizing any potential variability. It is purified to the highest standards, resulting in a highly pure and concentrated antibody solution.

The ICAD Polyclonal Antibody is supplied in a convenient and user-friendly format, allowing for easy handling and storage. It is provided in a liquid form, eliminating the need for reconstitution and ensuring immediate usability.

With its exceptional specificity, sensitivity, and reliability, the ICAD Polyclonal Antibody is an indispensable tool for researchers and scientists working in the field of cell biology and apoptosis. It offers unparalleled performance and accuracy, facilitating precise and reproducible results in a wide range of experimental settings.

Choose the ICAD Polyclonal Antibody for your research needs and unlock the potential of ICAD protein analysis with confidence and precision.