I12R2 Polyclonal Antibody

The protein encoded by this gene is a type I transmembrane protein identified as a subunit of the interleukin 12 receptor complex. The coexpression of this and IL12RB1 proteins was shown to lead to the formation of high-affinity IL12 binding sites and reconstitution of IL12 dependent signaling. The expression of this gene is up-regulated by interferon gamma in Th1 cells, and plays a role in Th1 cell differentiation. The up-regulation of this gene is found to be associated with a number of infectious diseases, such as Crohn's disease and leprosy, which is thought to contribute to the inflammatory response and host defense. Several transcript variants encoding different isoforms and non-protein coding transcripts have been found for this gene.

The I12R2 Polyclonal Antibody is a highly specific and sensitive immunological tool designed for the detection and quantification of the I12R2 protein. This antibody has been meticulously developed and rigorously validated to ensure optimal performance in various applications, including Western blotting, immunohistochemistry, and immunofluorescence.

The I12R2 Polyclonal Antibody exhibits exceptional affinity and selectivity towards the I12R2 protein, enabling accurate and reliable results. Its superior sensitivity allows for the detection of even low abundance levels of the target protein, making it an invaluable tool for researchers working with samples of limited availability or low expression.

This antibody has been produced using state-of-the-art techniques, ensuring batch-to-batch consistency and reproducibility. Its high specificity minimizes the risk of cross-reactivity with other proteins, enhancing the reliability of experimental data. Additionally, the I12R2 Polyclonal Antibody has been extensively tested on a wide range of sample types, including human, mouse, and rat tissues, guaranteeing its versatility and applicability across various research fields.

The I12R2 Polyclonal Antibody is supplied as a ready-to-use solution, eliminating the need for time-consuming and error-prone antibody preparation. Its user-friendly format allows for easy integration into laboratory workflows, saving valuable time and resources. Furthermore, this antibody is provided in a convenient storage format, ensuring long-term stability and preserving its functionality for extended periods.

In summary, the I12R2 Polyclonal Antibody is a highly reliable and efficient tool for the detection and quantification of the I12R2 protein. Its exceptional sensitivity, specificity, and versatility make it an indispensable asset for researchers in various scientific disciplines. With its user-friendly format and long-term stability, this antibody offers a seamless and robust solution for protein analysis, enabling groundbreaking discoveries and advancements in biomedical research.