HtrA2(Phospho Ser142) Polyclonal Antibody

This gene encodes a serine protease. The protein has been localized in the endoplasmic reticulum and interacts with an alternatively spliced form of mitogen-activated protein kinase 14. The protein has also been localized to the mitochondria with release to the cytosol following apoptotic stimulus. The protein is thought to induce apoptosis by binding the apoptosis inhibitory protein baculoviral IAP repeat-containing 4. Nuclear localization of this protein has also been observed. Alternate splicing of this gene results in multiple transcript variants encoding different isoforms.

The HtrA2(Phospho Ser142) Polyclonal Antibody is a highly specific and sensitive tool designed for the detection and quantification of HtrA2 protein phosphorylated at Ser142. This antibody is produced using advanced techniques and rigorous quality control measures to ensure optimal performance and reliability.

HtrA2, also known as high-temperature requirement protein A2, is a serine protease that plays a crucial role in various cellular processes, including apoptosis and protein quality control. Phosphorylation of HtrA2 at Ser142 has been implicated in the regulation of its enzymatic activity and subcellular localization.

The HtrA2(Phospho Ser142) Polyclonal Antibody has been extensively validated for its specificity and sensitivity in various experimental settings, including Western blotting, immunohistochemistry, and immunofluorescence. It exhibits minimal cross-reactivity with non-phosphorylated HtrA2 and other related proteins, ensuring accurate and reliable results.

This antibody is supplied as a liquid formulation in a convenient size, allowing for easy handling and storage. It is recommended for use in both basic research and clinical applications, providing valuable insights into the role of HtrA2 phosphorylation in disease processes and therapeutic interventions.

With its exceptional performance and reliability, the HtrA2(Phospho Ser142) Polyclonal Antibody is an indispensable tool for researchers and clinicians working in the fields of cell biology, molecular biology, and biomedical research.