HSF1(Phospho Thr142) Polyclonal Antibody

The product of this gene is a transcription factor that is rapidly induced after temperature stress and binds heat shock promoter elements (HSE). This protein plays a role in the regulation of lifespan. Expression of this gene is repressed by phsphorylation, which promotes binding by heat shock protein 90.

The HSF1(Phospho Thr142) Polyclonal Antibody is a highly specific and sensitive tool for the detection and quantification of HSF1 protein phosphorylated at threonine 142. This antibody has been rigorously validated for use in various applications, including Western blotting, immunohistochemistry, and immunofluorescence.

HSF1, also known as heat shock factor 1, is a transcription factor that plays a crucial role in the cellular response to stress, particularly heat stress. Phosphorylation of HSF1 at threonine 142 has been shown to regulate its activity and nuclear localization, making it an important target for studying the cellular stress response.

The HSF1(Phospho Thr142) Polyclonal Antibody has been carefully developed and optimized to ensure high specificity and sensitivity. It has been validated using a variety of experimental approaches, including siRNA knockdown and overexpression studies, to confirm its specificity for phosphorylated HSF1 at threonine 142.

This antibody is supplied as a liquid formulation, making it easy to use and compatible with a wide range of experimental protocols. It has been tested and validated for use in multiple species, including human, mouse, and rat, ensuring its versatility and applicability in various research settings.

In summary, the HSF1(Phospho Thr142) Polyclonal Antibody is a reliable and robust tool for the detection and quantification of phosphorylated HSF1 at threonine 142. Its high specificity, sensitivity, and versatility make it an essential reagent for researchers studying the cellular stress response and its implications in various biological processes.