BT Lab
SKU:BT-AP10114
hnRNP K(Phospho Ser216) Polyclonal Antibody
hnRNP K(Phospho Ser216) Polyclonal Antibody
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This gene belongs to the subfamily of ubiquitously expressed heterogeneous nuclear ribonucleoproteins (hnRNPs). The hnRNPs are RNA binding proteins and they complex with heterogeneous nuclear RNA (hnRNA). These proteins are associated with pre-mRNAs in the nucleus and appear to influence pre-mRNA processing and other aspects of mRNA metabolism and transport. While all of the hnRNPs are present in the nucleus, some seem to shuttle between the nucleus and the cytoplasm. The hnRNP proteins have distinct nucleic acid binding properties. The protein encoded by this gene is located in the nucleoplasm and has three repeats of KH domains that binds to RNAs. It is distinct among other hnRNP proteins in its binding preference; it binds tenaciously to poly(C). This protein is also thought to have a role during cell cycle progession. Several alternatively spliced transcript variants have
The hnRNP K(Phospho Ser216) Polyclonal Antibody is a highly specific and reliable tool designed for the detection and analysis of hnRNP K protein phosphorylated at Ser216. This antibody is produced using advanced techniques and high-quality materials to ensure optimal performance and accuracy in various applications, including Western blotting, immunoprecipitation, and immunofluorescence.
The hnRNP K protein plays a crucial role in RNA metabolism and regulation, and its phosphorylation at Ser216 has been implicated in various cellular processes, such as transcriptional regulation, mRNA splicing, and RNA transport. By targeting this specific phosphorylation site, our polyclonal antibody enables researchers to investigate the functional significance and molecular mechanisms underlying hnRNP K-mediated cellular processes.
This antibody exhibits exceptional sensitivity and specificity, allowing for the detection of hnRNP K(Phospho Ser216) with high precision and minimal background interference. It has been extensively validated using a variety of experimental approaches, ensuring reliable and reproducible results. Furthermore, it demonstrates excellent cross-reactivity with a wide range of species, making it suitable for use in diverse biological systems.
The hnRNP K(Phospho Ser216) Polyclonal Antibody is supplied as a liquid formulation in a convenient size, providing ample quantity for multiple experiments. It is recommended for use at a dilution range of 1:1000 to 1:5000, depending on the application and target species. Each batch of antibody undergoes rigorous quality control procedures to guarantee consistent performance and batch-to-batch reproducibility.
In summary, the hnRNP K(Phospho Ser216) Polyclonal Antibody is a valuable tool for researchers studying hnRNP K protein phosphorylation and its functional implications. With its exceptional sensitivity, specificity, and versatility, this antibody offers a reliable and accurate solution for investigating the intricate regulatory mechanisms of hnRNP K in various biological contexts.
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