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SKU:BT-AP10092

HNF-4 alpha (Acetyl Lys106) Polyclonal Antibody

HNF-4 alpha (Acetyl Lys106) Polyclonal Antibody

Regular price $275.00 USD
Regular price Sale price $275.00 USD
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The protein encoded by this gene is a nuclear transcription factor which binds DNA as a homodimer. The encoded protein controls the expression of several genes, including hepatocyte nuclear factor 1 alpha, a transcription factor which regulates the expression of several hepatic genes. This gene may play a role in development of the liver, kidney, and intestines. Mutations in this gene have been associated with monogenic autosomal dominant non-insulin-dependent diabetes mellitus type I. Alternative splicing of this gene results in multiple transcript variants encoding several different isoforms.

The HNF-4 alpha (Acetyl Lys106) Polyclonal Antibody is a highly specific and sensitive tool designed for the detection and quantification of HNF-4 alpha protein in various biological samples. This antibody has been developed using advanced techniques and is produced in a state-of-the-art facility to ensure exceptional quality and performance.

HNF-4 alpha, also known as Hepatocyte Nuclear Factor 4 alpha, is a transcription factor that plays a crucial role in the regulation of gene expression in the liver and other tissues. It is involved in various biological processes, including glucose and lipid metabolism, cell differentiation, and embryonic development. Dysregulation of HNF-4 alpha has been implicated in several diseases, such as diabetes, liver cancer, and metabolic disorders.

The HNF-4 alpha (Acetyl Lys106) Polyclonal Antibody has been specifically designed to target the acetylated form of HNF-4 alpha at Lys106, a critical site for its transcriptional activity. This antibody exhibits high affinity and specificity towards the acetylated form of HNF-4 alpha, enabling accurate detection and quantification of this modified protein.

This polyclonal antibody has been extensively validated using various experimental techniques, including Western blotting, immunohistochemistry, and immunofluorescence. It has demonstrated excellent performance in detecting endogenous levels of acetylated HNF-4 alpha in cell lysates, tissue sections, and other biological samples. The antibody shows minimal cross-reactivity with other proteins, ensuring reliable and specific results.

The HNF-4 alpha (Acetyl Lys106) Polyclonal Antibody is supplied as a liquid formulation, making it convenient and easy to use. It is provided in a ready-to-use format, eliminating the need for time-consuming and complex preparation steps. The antibody is suitable for use in various applications, including protein expression analysis, biomarker discovery, and drug development research.

In summary, the HNF-4 alpha (Acetyl Lys106) Polyclonal Antibody is a highly reliable and specific tool for the detection and quantification of acetylated HNF-4 alpha protein. With its exceptional quality and performance, this antibody is an invaluable asset for researchers and scientists working in the fields of molecular biology, biochemistry, and medicine.

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