HLAG Polyclonal Antibody

HLA-G belongs to the HLA class I heavy chain paralogues. This class I molecule is a heterodimer consisting of a heavy chain and a light chain (beta-2 microglobulin). The heavy chain is anchored in the membrane. HLA-G is expressed on fetal derived placental cells. The heavy chain is approximately 45 kDa and its gene contains 8 exons. Exon one encodes the leader peptide, exons 2 and 3 encode the alpha1 and alpha2 domain, which both bind the peptide, exon 4 encodes the alpha3 domain, exon 5 encodes the transmembrane region, and exon 6 encodes the cytoplasmic tail.

The HLAG Polyclonal Antibody is a highly specific and reliable tool designed for the detection and analysis of human leukocyte antigen G (HLA-G) protein. This antibody is produced using a polyclonal approach, ensuring a diverse range of antibodies that target different epitopes of the HLA-G protein.

The HLAG Polyclonal Antibody exhibits exceptional sensitivity and specificity, enabling accurate and precise identification of HLA-G in various biological samples. It has been extensively validated for use in immunohistochemistry (IHC), immunofluorescence (IF), and western blotting applications.

With its superior performance, the HLAG Polyclonal Antibody is an invaluable asset for researchers and clinicians involved in studying HLA-G expression and its role in immune tolerance, pregnancy, transplantation, and cancer. Its robust and consistent performance guarantees reliable and reproducible results, facilitating meaningful scientific discoveries and clinical advancements.

Furthermore, the HLAG Polyclonal Antibody is manufactured under stringent quality control measures, ensuring batch-to-batch consistency and reliability. It is supplied in a convenient and user-friendly format, allowing for easy handling and storage.

Choose the HLAG Polyclonal Antibody for its exceptional specificity, sensitivity, and reliability, and unlock new insights into the complex mechanisms of HLA-G biology.