Histone H4(Phospho Ser47) Polyclonal Antibody

Histones are basic nuclear proteins that are responsible for the nucleosome structure of the chromosomal fiber in eukaryotes. Two molecules of each of the four core histones (H2A, H2B, H3, and H4) form an octamer, around which approximately 146 bp of DNA is wrapped in repeating units, called nucleosomes. The linker histone, H1, interacts with linker DNA between nucleosomes and functions in the compaction of chromatin into higher order structures. This gene is intronless and encodes a replication-dependent histone that is a member of the histone H4 family. Transcripts from this gene lack polyA tails but instead contain a palindromic termination element. This gene is found in the histone microcluster on chromosome 6p21.33.

Histones are basic nuclear proteins that are responsible for the nucleosome structure of the chromosomal fiber in eukaryotes. Two molecules of each of the four core histones (H2A, H2B, H3, and H4) form an octamer, around which approximately 146 bp of DNA is wrapped in repeating units, called nucleosomes. The linker histone, H1, interacts with linker DNA between nucleosomes and functions in the compaction of chromatin into higher order structures. This gene is intronless and encodes a replication-dependent histone that is a member of the histone H4 family. Transcripts from this gene lack polyA tails but instead contain a palindromic termination element. This gene is found in the histone microcluster on chromosome 6p21.33.

The Histone H4(Phospho Ser47) Polyclonal Antibody is a highly specific and sensitive tool designed for the detection and analysis of phosphorylated Serine 47 residue on Histone H4 protein. This antibody is produced using advanced immunization techniques, ensuring high affinity and specificity towards the target antigen.

Histone H4 is a crucial component of chromatin structure and plays a vital role in gene regulation and DNA packaging. Phosphorylation of Serine 47 on Histone H4 has been implicated in various cellular processes, including DNA repair, cell cycle progression, and transcriptional regulation.

The Histone H4(Phospho Ser47) Polyclonal Antibody exhibits exceptional performance in various applications, such as Western blotting, immunohistochemistry, and immunofluorescence. It has been extensively validated for its specificity and sensitivity, ensuring reliable and reproducible results.

This antibody is supplied as a liquid formulation, ready to use for immediate experimentation. It is provided in a convenient size, allowing for multiple experiments without compromising the quality and performance.

Choose the Histone H4(Phospho Ser47) Polyclonal Antibody for your research needs and unlock the potential of studying the intricate mechanisms of histone modifications and their impact on cellular processes.