Histone H4 (Mono Methyl Lys21) Polyclonal Antibody

Histones are basic nuclear proteins that are responsible for the nucleosome structure of the chromosomal fiber in eukaryotes. Two molecules of each of the four core histones (H2A, H2B, H3, and H4) form an octamer, around which approximately 146 bp of DNA is wrapped in repeating units, called nucleosomes. The linker histone, H1, interacts with linker DNA between nucleosomes and functions in the compaction of chromatin into higher order structures. This gene is intronless and encodes a replication-dependent histone that is a member of the histone H4 family. Transcripts from this gene lack polyA tails but instead contain a palindromic termination element. This gene is found in the histone microcluster on chromosome 6p21.33.

The Histone H4 (Mono Methyl Lys21) Polyclonal Antibody is a highly specific and sensitive tool for the detection and analysis of histone H4 protein modifications. This antibody has been rigorously validated and exhibits exceptional performance in various applications, including Western blotting, immunoprecipitation, and immunofluorescence.

The Histone H4 (Mono Methyl Lys21) Polyclonal Antibody is produced using state-of-the-art techniques, ensuring high purity and batch-to-batch consistency. It has been affinity-purified using a peptide corresponding to the mono methylated Lys21 region of histone H4, resulting in a highly specific antibody that recognizes this modification with exceptional affinity.

This antibody demonstrates excellent sensitivity, allowing for the detection of even low levels of histone H4 mono methylation. Its high specificity ensures minimal cross-reactivity with other histone modifications or proteins, enabling accurate and reliable results.

The Histone H4 (Mono Methyl Lys21) Polyclonal Antibody is supplied as a ready-to-use solution, eliminating the need for time-consuming and error-prone antibody preparation. It is provided in a convenient format, allowing for easy storage and handling.

With its exceptional performance and reliability, the Histone H4 (Mono Methyl Lys21) Polyclonal Antibody is an indispensable tool for researchers studying histone modifications and their role in various biological processes. Its versatility and sensitivity make it suitable for a wide range of applications, facilitating groundbreaking discoveries in the field of epigenetics.