Histone H3(Phospho Tyr41) Polyclonal Antibody

Histones are basic nuclear proteins that are responsible for the nucleosome structure of the chromosomal fiber in eukaryotes. This structure consists of approximately 146 bp of DNA wrapped around a nucleosome, an octamer composed of pairs of each of the four core histones (H2A, H2B, H3, and H4). The chromatin fiber is further compacted through the interaction of a linker histone, H1, with the DNA between the nucleosomes to form higher order chromatin structures. This gene is intronless and encodes a replication-dependent histone that is a member of the histone H3 family. Transcripts from this gene lack polyA tails; instead, they contain a palindromic termination element. This gene is found in the large histone gene cluster on chromosome 6p22-p21.3.

The Histone H3(Phospho Tyr41) Polyclonal Antibody is a highly specific and sensitive tool designed for the detection and analysis of phosphorylated Tyr41 residue on Histone H3 protein. This antibody is produced using advanced immunization techniques and exhibits exceptional affinity and selectivity towards the phosphorylated form of Histone H3 at Tyr41.

Histone H3 is a crucial component of chromatin structure and plays a pivotal role in gene regulation and DNA packaging. Phosphorylation of Tyr41 on Histone H3 has been implicated in various cellular processes, including transcriptional activation, DNA repair, and cell cycle progression. Therefore, the ability to accurately detect and quantify this phosphorylation event is of utmost importance in understanding the underlying molecular mechanisms.

The Histone H3(Phospho Tyr41) Polyclonal Antibody offers outstanding performance in a wide range of applications, including Western blotting, immunohistochemistry, and immunofluorescence. It exhibits minimal cross-reactivity with non-phosphorylated forms of Histone H3, ensuring reliable and specific results. Furthermore, this antibody demonstrates excellent sensitivity, enabling the detection of low abundance phosphorylated Histone H3 species.

With its high quality and reliability, the Histone H3(Phospho Tyr41) Polyclonal Antibody is an indispensable tool for researchers and scientists studying epigenetics, chromatin biology, and cellular signaling pathways. Its exceptional performance and specificity make it an ideal choice for both basic research and clinical applications.

Order your Histone H3(Phospho Tyr41) Polyclonal Antibody today and unlock new insights into the intricate world of histone modifications and their impact on cellular processes.