Histone H3(Phospho Ser28) Polyclonal Antibody

Histones are basic nuclear proteins that are responsible for the nucleosome structure of the chromosomal fiber in eukaryotes. This structure consists of approximately 146 bp of DNA wrapped around a nucleosome, an octamer composed of pairs of each of the four core histones (H2A, H2B, H3, and H4). The chromatin fiber is further compacted through the interaction of a linker histone, H1, with the DNA between the nucleosomes to form higher order chromatin structures. This gene is intronless and encodes a replication-dependent histone that is a member of the histone H3 family. Transcripts from this gene lack polyA tails; instead, they contain a palindromic termination element. This gene is found in the large histone gene cluster on chromosome 6p22-p21.3.

Introducing the Histone H3 Phospho-Ser28 Polyclonal Antibody, a cutting-edge product meticulously developed by BT Lab, available exclusively through Dana Biosciences. This highly specialized antibody is designed to detect and analyze the phosphorylation of serine 28 residue on histone H3, a crucial post-translational modification associated with various cellular processes.

Crafted with utmost precision and utilizing state-of-the-art technology, the Histone H3 Phospho-Ser28 Polyclonal Antibody offers exceptional sensitivity and specificity, ensuring accurate and reliable results in your research endeavors. Its superior affinity for the phosphorylated serine 28 epitope enables precise identification and quantification of this critical histone modification.

This antibody is meticulously validated through rigorous quality control measures, guaranteeing optimal performance and reproducibility. Its exceptional specificity ensures minimal cross-reactivity with non-phosphorylated histone H3 or other phosphorylation sites, thereby enhancing the accuracy of your experimental outcomes.

The Histone H3 Phospho-Ser28 Polyclonal Antibody is compatible with a wide range of applications, including immunoblotting, immunoprecipitation, immunofluorescence, and chromatin immunoprecipitation. Its versatility allows for comprehensive investigation of histone H3 phosphorylation dynamics in diverse biological contexts.

With its user-friendly protocol and comprehensive technical support, this antibody offers a seamless experience in your laboratory. Its robust performance, coupled with the expertise of BT Lab and the trusted distribution network of Dana Biosciences, ensures that you receive a product of unparalleled quality and reliability.

In summary, the Histone H3 Phospho-Ser28 Polyclonal Antibody by BT Lab, available exclusively through Dana Biosciences, is a cutting-edge tool for researchers seeking to unravel the intricate mechanisms of histone H3 phosphorylation. With its exceptional sensitivity, specificity, and compatibility with various applications, this antibody empowers scientists to delve deeper into the fascinating world of epigenetics and chromatin biology.