Histone H3(Phospho Ser28) Polyclonal Antibody

Histones are basic nuclear proteins that are responsible for the nucleosome structure of the chromosomal fiber in eukaryotes. This structure consists of approximately 146 bp of DNA wrapped around a nucleosome, an octamer composed of pairs of each of the four core histones (H2A, H2B, H3, and H4). The chromatin fiber is further compacted through the interaction of a linker histone, H1, with the DNA between the nucleosomes to form higher order chromatin structures. This gene is intronless and encodes a replication-dependent histone that is a member of the histone H3 family. Transcripts from this gene lack polyA tails; instead, they contain a palindromic termination element. This gene is found in the large histone gene cluster on chromosome 6p22-p21.3.

The Histone H3(Phospho Ser28) Polyclonal Antibody is a highly specific and sensitive tool designed for the detection and analysis of phosphorylated Serine 28 residue on Histone H3 protein. This antibody is produced using advanced immunization techniques, ensuring high affinity and specificity towards the target antigen.

Histone H3 is a crucial protein involved in chromatin structure and gene regulation. Phosphorylation of Serine 28 on Histone H3 has been implicated in various cellular processes, including DNA damage response, cell cycle regulation, and transcriptional activation. Therefore, the detection and quantification of phosphorylated Serine 28 on Histone H3 is of great importance in understanding these biological processes.

The Histone H3(Phospho Ser28) Polyclonal Antibody has been rigorously validated for its specificity and sensitivity through various experimental approaches, including Western blotting, immunohistochemistry, and immunofluorescence. It exhibits minimal cross-reactivity with non-phosphorylated Histone H3 and other related proteins, ensuring accurate and reliable results.

This antibody is supplied as a liquid formulation, ready to use for various applications in molecular biology and cell biology research. It is suitable for use in both qualitative and quantitative assays, enabling the precise measurement of phosphorylated Serine 28 on Histone H3 in various sample types, including cell lysates, tissue extracts, and purified proteins.

With its exceptional performance and reliability, the Histone H3(Phospho Ser28) Polyclonal Antibody is an indispensable tool for researchers studying epigenetics, chromatin biology, and cellular signaling pathways. Its high specificity and sensitivity make it an ideal choice for elucidating the role of phosphorylated Serine 28 on Histone H3 in various biological processes and disease states.

The Histone H3(Phospho Ser28) Polyclonal Antibody is a highly specific and sensitive tool designed for the detection and analysis of phosphorylated Serine 28 residue on Histone H3 protein. This antibody is produced using advanced immunization techniques, ensuring high affinity and specificity towards the target antigen.

Histone H3 is a crucial protein involved in chromatin structure and gene regulation. Phosphorylation of Serine 28 on Histone H3 has been implicated in various cellular processes, including DNA damage response, cell cycle regulation, and transcriptional activation. Therefore, the detection and quantification of phosphorylated Serine 28 on Histone H3 are of great importance in understanding these biological processes.

The Histone H3(Phospho Ser28) Polyclonal Antibody exhibits exceptional sensitivity and specificity, enabling accurate and reliable detection of phosphorylated Serine 28 on Histone H3 in various sample types, including cell lysates and tissue sections. This antibody has been extensively validated in multiple experimental techniques, such as Western blotting, immunohistochemistry, and immunofluorescence, ensuring its versatility and applicability in diverse research settings.

With its superior performance and reliability, the Histone H3(Phospho Ser28) Polyclonal Antibody is an indispensable tool for researchers studying epigenetics, chromatin biology, and cellular signaling pathways. Its high specificity and sensitivity make it an ideal choice for investigating the role of phosphorylated Serine 28 on Histone H3 in various biological processes and disease states.

Order the Histone H3(Phospho Ser28) Polyclonal Antibody today and unlock new insights into the intricate mechanisms of gene regulation and cellular function.