Histone H2A(Phospho Thr121) Polyclonal Antibody

Histones are basic nuclear proteins that are responsible for the nucleosome structure of the chromosomal fiber in eukaryotes. Two molecules of each of the four core histones (H2A, H2B, H3, and H4) form an octamer, around which approximately 146 bp of DNA is wrapped in repeating units, called nucleosomes. The linker histone, H1, interacts with linker DNA between nucleosomes and functions in the compaction of chromatin into higher order structures. This gene is intronless and encodes a replication-dependent histone that is a member of the histone H2A family. Transcripts from this gene lack polyA tails but instead contain a palindromic termination element. This gene is found in the small histone gene cluster on chromosome 6p22-p21.3.

The Histone H2A(Phospho Thr121) Polyclonal Antibody is a highly specific and sensitive tool designed for the detection and analysis of phosphorylated Histone H2A at Thr121 residue. This antibody is produced using advanced immunization techniques and exhibits exceptional affinity and selectivity towards the phosphorylated form of Histone H2A.

Histone H2A is a crucial component of the nucleosome, which is the basic unit of chromatin structure. Phosphorylation of Histone H2A at Thr121 has been implicated in various cellular processes, including DNA repair, transcriptional regulation, and cell cycle progression. Therefore, the ability to accurately detect and quantify the phosphorylated form of Histone H2A is of utmost importance in understanding the intricate mechanisms underlying these biological processes.

The Histone H2A(Phospho Thr121) Polyclonal Antibody offers outstanding performance in a wide range of applications, including Western blotting, immunoprecipitation, and immunofluorescence. It has been rigorously validated for its specificity and sensitivity, ensuring reliable and reproducible results. Furthermore, this antibody has been extensively tested on various cell lines and tissues, demonstrating its versatility and robustness.

With its exceptional quality and reliability, the Histone H2A(Phospho Thr121) Polyclonal Antibody is an indispensable tool for researchers and scientists working in the fields of epigenetics, chromatin biology, and cellular signaling. Its ability to specifically detect and quantify the phosphorylated form of Histone H2A at Thr121 residue opens up new avenues for understanding the complex regulatory networks governing gene expression and genome stability.

Order your Histone H2A(Phospho Thr121) Polyclonal Antibody today and unlock the potential of phosphorylated Histone H2A in your research endeavors.