GSTM1 Polyclonal Antibody

Cytosolic and membrane-bound forms of glutathione S-transferase are encoded by two distinct supergene families. At present, eight distinct classes of the soluble cytoplasmic mammalian glutathione S-transferases have been identified: alpha, kappa, mu, omega, pi, sigma, theta and zeta. This gene encodes a glutathione S-transferase that belongs to the mu class. The mu class of enzymes functions in the detoxification of electrophilic compounds, including carcinogens, therapeutic drugs, environmental toxins and products of oxidative stress, by conjugation with glutathione. The genes encoding the mu class of enzymes are organized in a gene cluster on chromosome 1p13.3 and are known to be highly polymorphic. These genetic variations can change an individual's susceptibility to carcinogens and toxins as well as affect the toxicity and efficacy of certain drugs. Null mutations of this class mu g

The GSTM1 Polyclonal Antibody is a highly specific and sensitive tool designed for the detection and quantification of Glutathione S-transferase Mu 1 (GSTM1) protein. This antibody is produced using advanced immunization techniques, ensuring high affinity and specificity towards the target protein.

GSTM1 is a member of the glutathione S-transferase family, which plays a crucial role in the detoxification of xenobiotics and endogenous compounds. It is primarily expressed in the liver, lung, and kidney tissues. Aberrant expression or dysfunction of GSTM1 has been associated with various diseases, including cancer, neurodegenerative disorders, and drug resistance.

The GSTM1 Polyclonal Antibody is validated for multiple applications, including Western blotting, immunohistochemistry, and immunofluorescence. It exhibits excellent performance in various sample types, such as cell lysates, tissue homogenates, and biological fluids. This antibody demonstrates high sensitivity and specificity, enabling accurate and reliable detection of GSTM1 protein levels.

With its superior quality and performance, the GSTM1 Polyclonal Antibody is an indispensable tool for researchers and clinicians involved in studying the role of GSTM1 in various physiological and pathological processes. Its application in diagnostic and therapeutic research holds great potential for advancing our understanding and treatment of diseases associated with GSTM1 dysregulation.

Order the GSTM1 Polyclonal Antibody today and unlock new insights into the intricate mechanisms governed by GSTM1, paving the way for innovative approaches in disease diagnosis, prognosis, and treatment.