GRK2(Phospho-Tyr86) Polyclonal Antibody

The product of this gene phosphorylates the beta-2-adrenergic receptor and appears to mediate agonist-specific desensitization observed at high agonist concentrations. This protein is an ubiquitous cytosolic enzyme that specifically phosphorylates the activated form of the beta-adrenergic and related G-protein-coupled receptors. Abnormal coupling of beta-adrenergic receptor to G protein is involved in the pathogenesis of the failing heart.

The GRK2(Phospho-Tyr86) Polyclonal Antibody is a highly specific and sensitive tool designed for the detection and quantification of GRK2 protein phosphorylated at tyrosine 86. This antibody is produced using advanced techniques and high-quality materials to ensure optimal performance and reliability.

GRK2, also known as G protein-coupled receptor kinase 2, plays a crucial role in regulating the signaling pathways of G protein-coupled receptors (GPCRs). Phosphorylation of GRK2 at tyrosine 86 has been implicated in various cellular processes, including receptor desensitization and internalization.

The GRK2(Phospho-Tyr86) Polyclonal Antibody exhibits exceptional specificity towards the phosphorylated form of GRK2 at tyrosine 86, enabling accurate detection and quantification of this important post-translational modification. This antibody has been extensively validated in various experimental settings, including Western blotting, immunoprecipitation, and immunofluorescence.

With its high sensitivity and specificity, the GRK2(Phospho-Tyr86) Polyclonal Antibody is an invaluable tool for researchers studying GPCR signaling pathways and investigating the role of GRK2 phosphorylation in various cellular processes. Its reliable performance and reproducibility make it an ideal choice for both basic research and drug development applications.

Order your GRK2(Phospho-Tyr86) Polyclonal Antibody today and unlock new insights into the intricate mechanisms of GPCR signaling.