Gremlin-2 Polyclonal Antibody

This gene encodes a member of the BMP (bone morphogenic protein) antagonist family. Like BMPs, BMP antagonists contain cystine knots and typically form homo- and heterodimers. The CAN (cerberus and dan) subfamily of BMP antagonists, to which this gene belongs, is characterized by a C-terminal cystine knot with an eight-membered ring. The antagonistic effect of the secreted glycosylated protein encoded by this gene is likely due to its direct binding to BMP proteins. As an antagonist of BMP, this gene may play a role in regulating organogenesis, body patterning, and tissue differentiation.

The Gremlin-2 Polyclonal Antibody is a highly specific and sensitive antibody designed for the detection of Gremlin-2 protein in various biological samples. This antibody is produced by immunizing rabbits with a synthetic peptide corresponding to the C-terminal region of human Gremlin-2 protein. The resulting polyclonal antibody has been purified using protein A affinity chromatography and is suitable for use in various applications, including Western blotting, immunohistochemistry, and ELISA.

The Gremlin-2 Polyclonal Antibody has been extensively validated for its specificity and sensitivity in detecting Gremlin-2 protein in various tissues and cell lines. It has been shown to exhibit minimal cross-reactivity with other related proteins, ensuring accurate and reliable results. This antibody is also highly reproducible, providing consistent results across multiple experiments.

The Gremlin-2 Polyclonal Antibody is supplied as a liquid formulation in phosphate-buffered saline (PBS) with 0.02% sodium azide as a preservative. It is available in various sizes to meet the needs of different research applications. This antibody is suitable for use in both basic and clinical research, including studies of developmental biology, cancer, and cardiovascular disease.

In summary, the Gremlin-2 Polyclonal Antibody is a highly specific and sensitive antibody that is ideal for the detection of Gremlin-2 protein in various biological samples. Its high specificity, sensitivity, and reproducibility make it an essential tool for researchers studying the role of Gremlin-2 in various biological processes.