Granzyme B Polyclonal Antibody

This gene encodes a member of the granzyme subfamily of proteins, part of the peptidase S1 family of serine proteases. The encoded preproprotein is secreted by natural killer (NK) cells and cytotoxic T lymphocytes (CTLs) and proteolytically processed to generate the active protease, which induces target cell apoptosis. This protein also processes cytokines and degrades extracellular matrix proteins, and these roles are implicated in chronic inflammation and wound healing. Expression of this gene may be elevated in human patients with cardiac fibrosis.

The Granzyme B Polyclonal Antibody is a highly specific and sensitive tool designed for the detection and quantification of Granzyme B protein in various biological samples. This antibody is produced by immunizing rabbits with a synthetic peptide corresponding to a specific region of the Granzyme B protein. It has been extensively validated for its specificity and sensitivity through various experimental approaches, including Western blotting, immunohistochemistry, and immunofluorescence.

The Granzyme B Polyclonal Antibody exhibits exceptional performance in detecting endogenous levels of Granzyme B protein in human, mouse, and rat tissues. It recognizes a single band of the expected molecular weight in Western blot analysis, indicating its high specificity. Furthermore, it demonstrates minimal cross-reactivity with other related proteins, ensuring accurate and reliable results.

This antibody is supplied as a liquid formulation in a convenient size, allowing for easy handling and storage. It is provided in a ready-to-use format, eliminating the need for additional reagents or preparation steps. The Granzyme B Polyclonal Antibody is suitable for a wide range of applications, including but not limited to, protein expression analysis, disease research, and drug development.

In summary, the Granzyme B Polyclonal Antibody is a valuable tool for researchers in the field of immunology and molecular biology. Its high specificity, sensitivity, and ease of use make it an ideal choice for studying the role of Granzyme B in various biological processes and diseases.