GPX1 Polyclonal Antibody

The protein encoded by this gene belongs to the glutathione peroxidase family, members of which catalyze the reduction of organic hydroperoxides and hydrogen peroxide (H2O2) by glutathione, and thereby protect cells against oxidative damage. Other studies indicate that H2O2 is also essential for growth-factor mediated signal transduction, mitochondrial function, and maintenance of thiol redox-balance; therefore, by limiting H2O2 accumulation, glutathione peroxidases are also involved in modulating these processes. Several isozymes of this gene family exist in vertebrates, which vary in cellular location and substrate specificity. This isozyme is the most abundant, is ubiquitously expressed and localized in the cytoplasm, and whose preferred substrate is hydrogen peroxide. It is also a selenoprotein, containing the rare amino acid selenocysteine (Sec) at its active site. Sec is encoded by the UGA cod

The GPX1 Polyclonal Antibody is a highly specific and sensitive tool designed for the detection and quantification of Glutathione Peroxidase 1 (GPX1) protein in various biological samples. This antibody has been meticulously developed and rigorously validated to ensure optimal performance and reliability.

GPX1 is a crucial enzyme involved in the cellular defense against oxidative stress. It plays a pivotal role in the detoxification of hydrogen peroxide and lipid peroxides, thereby protecting cells from oxidative damage. Dysregulation of GPX1 has been implicated in various pathological conditions, including cancer, neurodegenerative diseases, and cardiovascular disorders.

The GPX1 Polyclonal Antibody exhibits exceptional specificity, binding exclusively to GPX1 protein without cross-reactivity to other related proteins. It has been extensively tested in a variety of experimental settings, including Western blotting, immunohistochemistry, and immunofluorescence, consistently yielding robust and reproducible results.

This antibody is produced using state-of-the-art recombinant DNA technology, ensuring high purity and batch-to-batch consistency. It is supplied as a liquid formulation, ready for immediate use, and is compatible with a wide range of sample types, including cell lysates, tissue homogenates, and serum.

The GPX1 Polyclonal Antibody is an indispensable tool for researchers and clinicians investigating the role of GPX1 in oxidative stress-related diseases. Its exceptional sensitivity and specificity make it an ideal choice for accurate and reliable protein quantification. Trust in the GPX1 Polyclonal Antibody to enhance your research and advance our understanding of cellular defense mechanisms against oxidative stress.