GDF1 Polyclonal Antibody

This gene encodes a secreted ligand of the TGF-beta (transforming growth factor-beta) superfamily of proteins. Ligands of this family bind various TGF-beta receptors leading to recruitment and activation of SMAD family transcription factors that regulate gene expression. The encoded preproprotein is proteolytically processed to generate each subunit of the disulfide-linked homodimer. Studies in rodents suggest that this protein is involved in the establishment of left-right asymmetry in early embryogenesis and in neural development in later embryogenesis. The encoded protein is translated from a bicistronic mRNA that also encodes ceramide synthase 1. Mutations in this gene are associated with several congenital cardiovascular malformations.

The GDF1 Polyclonal Antibody is a highly specific and sensitive antibody designed for the detection of Growth Differentiation Factor 1 (GDF1) in various biological samples. This antibody is produced by immunizing rabbits with a synthetic peptide corresponding to the C-terminal region of human GDF1 protein. The resulting polyclonal antibody has been purified using protein A affinity chromatography and is suitable for use in various applications, including Western blotting, immunohistochemistry, and ELISA.

The GDF1 Polyclonal Antibody has been extensively validated for its specificity and sensitivity in detecting GDF1 protein in various tissues and cell lines. It has been shown to recognize both the mature and precursor forms of GDF1 protein, making it a versatile tool for studying the expression and regulation of GDF1 in different biological systems.

This antibody is supplied as a liquid formulation in phosphate-buffered saline (PBS) with 0.02% sodium azide as a preservative. It is recommended to store the antibody at -20°C for long-term storage and to avoid repeated freeze-thaw cycles.

In summary, the GDF1 Polyclonal Antibody is a reliable and high-quality tool for the detection of GDF1 protein in various biological samples. Its specificity and sensitivity make it an ideal choice for researchers studying the role of GDF1 in development, disease, and other biological processes.