GALR2 Polyclonal Antibody

Galanin is an important neuromodulator present in the brain, gastrointestinal system, and hypothalamopituitary axis. It is a 30-amino acid non-C-terminally amidated peptide that potently stimulates growth hormone secretion, inhibits cardiac vagal slowing of heart rate, abolishes sinus arrhythmia, and inhibits postprandial gastrointestinal motility. The actions of galanin are mediated through interaction with specific membrane receptors that are members of the 7-transmembrane family of G protein-coupled receptors. GALR2 interacts with the N-terminal residues of the galanin peptide. The primary signaling mechanism for GALR2 is through the phospholipase C/protein kinase C pathway (via Gq), in contrast to GALR1, which communicates its intracellular signal by inhibition of adenylyl cyclase through Gi. However, it has been demonstrated that GALR2 couples efficiently to both the Gq and Gi proteins to simul

The GALR2 Polyclonal Antibody is a highly specific and sensitive tool designed for the detection and analysis of the Galanin receptor 2 (GALR2) protein. This antibody is produced using advanced techniques and rigorous quality control measures to ensure optimal performance and reliability.

The GALR2 Polyclonal Antibody exhibits exceptional affinity and selectivity towards GALR2, making it an ideal choice for various applications, including immunohistochemistry, western blotting, and flow cytometry. It recognizes both the native and recombinant forms of GALR2, enabling accurate and precise quantification of the protein in various biological samples.

With its superior sensitivity, this antibody allows for the detection of GALR2 even at low expression levels, facilitating the study of GALR2 in diverse research areas, such as neuroscience, endocrinology, and cancer biology. Its robust performance ensures consistent and reproducible results, enabling researchers to obtain reliable data for their experiments.

The GALR2 Polyclonal Antibody is supplied in a convenient and ready-to-use format, eliminating the need for time-consuming and complex preparation steps. It is provided in a liquid formulation, allowing for easy handling and minimizing the risk of sample contamination.

Furthermore, this antibody has been extensively validated and characterized to ensure its specificity and reliability. It has been tested against a wide range of species, including human, mouse, and rat, guaranteeing its broad applicability across different experimental models.

In summary, the GALR2 Polyclonal Antibody is a high-quality research tool that offers exceptional sensitivity, specificity, and reliability for the detection and analysis of GALR2 protein. Its advanced features and rigorous quality control measures make it an indispensable asset for researchers in various fields, enabling them to advance their understanding of GALR2 biology and its implications in health and disease.