GABAA R beta 1(Phospho Ser434) Polyclonal Antibody

The gamma-aminobutyric acid (GABA) A receptor is a multisubunit chloride channel that mediates the fastest inhibitory synaptic transmission in the central nervous system. This gene encodes GABA A receptor, beta 1 subunit. It is mapped to chromosome 4p12 in a cluster comprised of genes encoding alpha 4, alpha 2 and gamma 1 subunits of the GABA A receptor. Alteration of this gene is implicated in the pathogenetics of schizophrenia.

The GABAA R beta 1(Phospho Ser434) Polyclonal Antibody is a highly specific and reliable tool designed for the detection and analysis of GABAA receptor beta 1 subunit phosphorylated at Serine 434. This antibody is produced using advanced polyclonal antibody technology, ensuring high affinity and specificity towards the target protein.

The GABAA receptor beta 1 subunit plays a crucial role in the functioning of the GABAA receptor, a ligand-gated ion channel that mediates inhibitory neurotransmission in the central nervous system. Phosphorylation of the beta 1 subunit at Serine 434 has been implicated in the regulation of receptor activity and synaptic plasticity.

This polyclonal antibody has been extensively validated for its performance in various applications, including Western blotting, immunohistochemistry, and immunofluorescence. It exhibits exceptional sensitivity and selectivity, enabling accurate and reproducible detection of the phosphorylated GABAA receptor beta 1 subunit.

With its superior quality and reliability, the GABAA R beta 1(Phospho Ser434) Polyclonal Antibody is an indispensable tool for researchers studying the molecular mechanisms underlying GABAA receptor signaling and its modulation in various physiological and pathological conditions.