FoxO4(Phospho Ser197) Polyclonal Antibody

This gene encodes a member of the O class of winged helix/forkhead transcription factor family. Proteins encoded by this class are regulated by factors involved in growth and differentiation indicating they play a role in these processes. A translocation involving this gene on chromosome X and the homolog of the Drosophila trithorax gene, encoding a DNA binding protein, located on chromosome 11 is associated with leukemia. Multiple transcript variants encoding different isoforms have been found for this gene.

The FoxO4(Phospho Ser197) Polyclonal Antibody is a highly specific and sensitive tool designed for the detection and quantification of FoxO4 protein phosphorylated at Ser197. This antibody is produced using advanced techniques and high-quality materials to ensure optimal performance and reliability.

The FoxO4 protein is a member of the Forkhead box O (FoxO) transcription factor family, which plays a crucial role in various cellular processes, including cell cycle regulation, apoptosis, and oxidative stress response. Phosphorylation of FoxO4 at Ser197 has been shown to modulate its activity and subcellular localization, making it an important target for research in the field of cell biology and signal transduction.

This polyclonal antibody is raised in rabbits using a synthetic phospho-peptide corresponding to the phosphorylation site at Ser197 of FoxO4. It has been extensively validated for specificity and sensitivity through various experimental approaches, including Western blotting, immunoprecipitation, and immunofluorescence.

The FoxO4(Phospho Ser197) Polyclonal Antibody exhibits excellent performance in detecting phosphorylated FoxO4 protein in a wide range of sample types, including cell lysates, tissue extracts, and cultured cells. It provides reliable and reproducible results, enabling accurate quantification of FoxO4 phosphorylation levels.

With its high specificity and sensitivity, this antibody is an invaluable tool for researchers studying the role of FoxO4 in cellular processes and its potential implications in various diseases, such as cancer, neurodegenerative disorders, and aging. It offers a reliable means of investigating the regulation and function of FoxO4, contributing to a better understanding of its biological significance.

In summary, the FoxO4(Phospho Ser197) Polyclonal Antibody is a top-quality research reagent that enables precise detection and quantification of phosphorylated FoxO4 protein. Its exceptional performance and reliability make it an essential tool for scientists engaged in cell biology, signal transduction, and disease research.