Flt-3(Phospho Tyr842) Polyclonal Antibody

This gene encodes a class III receptor tyrosine kinase that regulates hematopoiesis. This receptor is activated by binding of the fms-related tyrosine kinase 3 ligand to the extracellular domain, which induces homodimer formation in the plasma membrane leading to autophosphorylation of the receptor. The activated receptor kinase subsequently phosphorylates and activates multiple cytoplasmic effector molecules in pathways involved in apoptosis, proliferation, and differentiation of hematopoietic cells in bone marrow. Mutations that result in the constitutive activation of this receptor result in acute myeloid leukemia and acute lymphoblastic leukemia.

The FLT-3(PHOSPHO TYR842) Polyclonal Antibody is a highly specific and reliable tool designed for the detection and analysis of FLT-3 protein phosphorylated at tyrosine 842. This antibody is produced using advanced polyclonal antibody technology, ensuring exceptional sensitivity and specificity in various applications, including Western blotting, immunoprecipitation, and immunohistochemistry.

The FLT-3(PHOSPHO TYR842) Polyclonal Antibody exhibits excellent performance in detecting the phosphorylation status of FLT-3 at tyrosine 842, a critical residue involved in the activation and signaling of FLT-3 receptor tyrosine kinase. This antibody enables researchers to investigate the activation and downstream signaling pathways of FLT-3, facilitating a deeper understanding of its role in cellular processes and disease development.

With its high affinity and selectivity, the FLT-3(PHOSPHO TYR842) Polyclonal Antibody offers exceptional sensitivity and specificity, ensuring accurate and reliable results. Its robust performance allows for the detection of even low levels of phosphorylated FLT-3, making it an ideal choice for both basic research and clinical applications.

The FLT-3(PHOSPHO TYR842) Polyclonal Antibody is supplied in a convenient and ready-to-use format, ensuring ease of use and saving valuable time in the laboratory. It has been extensively validated and quality-controlled to ensure consistent and reproducible results, providing researchers with confidence in their experiments.

In summary, the FLT-3(PHOSPHO TYR842) Polyclonal Antibody is a highly specific and reliable tool for the detection and analysis of FLT-3 protein phosphorylated at tyrosine 842. Its exceptional sensitivity, specificity, and convenience make it an invaluable asset for researchers studying FLT-3 signaling pathways and its implications in various diseases.