Flt-1(Phospho Tyr1213) Polyclonal Antibody

This gene encodes a member of the vascular endothelial growth factor receptor (VEGFR) family. VEGFR family members are receptor tyrosine kinases (RTKs) which contain an extracellular ligand-binding region with seven immunoglobulin (Ig)-like domains, a transmembrane segment, and a tyrosine kinase (TK) domain within the cytoplasmic domain. This protein binds to VEGFR-A, VEGFR-B and placental growth factor and plays an important role in angiogenesis and vasculogenesis. Expression of this receptor is found in vascular endothelial cells, placental trophoblast cells and peripheral blood monocytes. Multiple transcript variants encoding different isoforms have been found for this gene. Isoforms include a full-length transmembrane receptor isoform and shortened, soluble isoforms. The soluble isoforms are associated with the onset of pre-eclampsia.

The Flt-1(Phospho Tyr1213) Polyclonal Antibody is a highly specific and sensitive tool designed for the detection and quantification of Flt-1 protein phosphorylated at Tyr1213. This antibody is produced using advanced polyclonal antibody technology, ensuring high affinity and specificity towards the target protein.

Flt-1, also known as vascular endothelial growth factor receptor 1 (VEGFR-1), plays a crucial role in angiogenesis and vascular development. Phosphorylation of Flt-1 at Tyr1213 is a key event in the activation of downstream signaling pathways involved in angiogenesis regulation.

The Flt-1(Phospho Tyr1213) Polyclonal Antibody has been rigorously validated for its performance in various applications, including Western blotting, immunohistochemistry, and immunofluorescence. It exhibits exceptional sensitivity and specificity, enabling accurate and reliable detection of phosphorylated Flt-1 in complex biological samples.

This antibody is supplied as a liquid formulation, ready for immediate use. It is provided in a convenient size, ensuring cost-effectiveness and minimizing waste. The Flt-1(Phospho Tyr1213) Polyclonal Antibody is compatible with a wide range of experimental conditions and can be used in both research and clinical settings.

Choose the Flt-1(Phospho Tyr1213) Polyclonal Antibody for your research needs and unlock new insights into the role of Flt-1 phosphorylation in angiogenesis and vascular development. Trust in its exceptional performance and reliability to advance your scientific discoveries.